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maleic acid (maleate)

RN given refers to parent cpd(Z)-isomer which is maleic acid; all RR's given refer to (Z)-isomer; (E)-isomer is fumaric acid
Also Known As:
maleate; hydrogen maleate; maleic acid, ammonium salt; maleic acid, calcium salt; maleic acid, dipotassium salt; maleic acid, disodium salt; maleic acid, iron salt; maleic acid, monoammonium salt; maleic acid, monocopper (2+) salt; maleic acid, monosodium salt; maleic acid, neodymium salt; maleic acid, potassium salt; maleic acid, sodium salt; sodium maleate; but-2-enedioic acid
Networked: 370 relevant articles (25 outcomes, 53 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Maeda, Hiroshi: 9 articles (07/2015 - 03/2002)
2. Greish, Khaled: 6 articles (09/2015 - 01/2005)
3. Zager, Richard A: 5 articles (11/2015 - 01/2008)
4. Fang, Jun: 4 articles (08/2014 - 01/2005)
5. DeVizio, William: 4 articles (04/2011 - 02/2002)
6. Goossens, An: 3 articles (11/2015 - 11/2006)
7. Christophi, Chris: 3 articles (07/2015 - 01/2009)
8. Malcontenti-Wilson, Cathy: 3 articles (07/2015 - 01/2009)
9. Daruwalla, Jurstine: 3 articles (07/2015 - 01/2009)
10. Muralidharan, Vijayaragavan: 3 articles (07/2015 - 01/2009)

Related Diseases

1. Smear Layer
2. Neoplasms (Cancer)
3. Gingivitis
12/01/1992 - "A total of 159 adult male and female subjects between 18 and 63 years of age, were entered into a 6-month, double-blind clinical study to assess the effects of a dentifrice containing 0.3% triclosan and 2% of a copolymer of methoxyethylene and maleic acid on supragingival plaque formation and gingivitis, as compared to a placebo dentifrice. "
11/01/1991 - "A total of one hundred twenty-one (121) adult male and female subjects completed a 6-month, double-blind clinical study comparing the effect on supragingival plaque formation and gingivitis of a dentifrice containing 0.3% Triclosan and 2.0% of a copolymer of methoxyethylene and maleic acid to a placebo dentifrice. "
09/01/1990 - "A total of 108 adult male and female subjects completed a 7-month, double-blind clinical study designed to compare the effect of a dentifrice containing 0.3% triclosan and 2% of a copolymer of methoxyethylene and maleic acid on plaque formation and gingivitis, as compared to a placebo dentifrice. "
09/01/1989 - "One hundred eighteen male and female adult subjects were entered into a 14-week, double-blind clinical study to compare the effect of a dentifrice containing 0.3% triclosan and 2% of a copolymer of methoxyethylene and maleic acid on plaque formation and gingivitis. "
02/01/1995 - "A 6-month, single-blind and parallel clinical study was conducted to compare the effects of dentifrice containing 0.3% triclosan and 2.0% of copolymer (methoxyethylene and maleic acid) with a customary oral hygiene procedure on supragingival plaque formation and gingivitis. "
4. Fanconi Syndrome (Syndrome, Fanconi)
5. Seizures (Seizure)
07/01/2006 - "Use of acepromazine (i.e., acetylpromazine) maleate in dogs with a history of seizures is reportedly contraindicated because of the risk of decreasing the seizure threshold in these animals. "
12/01/2005 - "The NMDA receptor antagonist (+)-5-methyl-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5,10-imine maleate (MK-801), administered intraperitoneally 30 or 60 but not 120 min after 4-AP perfusion, when animals show intense electroencephalography epileptiform activity, prevented the delayed neurodegeneration whereas the seizures continued for about 3 h as in the control animals. "
06/30/2009 - "Subeffective doses of 3-ASP plus diazepam, 5S,10R-(+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate (MK-801) or 6,7-dinitroquinoxaline-2,3-dione (DNQX) increased the latency to the seizure onset induced by PC, suggesting the involvement of ionotropic glutamatergic and GABAergic receptors in anticonvulsant action of 3-ASP. "
07/31/1992 - "Seven days after the last amygdala kindled seizure, [3H](+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10- imine maleate ([3H]MK-801) binding, which labels N-methyl-D-aspartate (NMDA)-sensitive receptor-linked cation channels, decreased significantly only in the amygdala of kindled rats compared to that of controls under equilibrium assay conditions. "
08/11/1989 - "In an electrographic model of seizures in the hippocampal slice, both of the N-methyl-D-aspartate (NMDA) antagonists 2-amino-5-phosphonovaleric acid and 5-methyl-10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5,10-imine maleate (MK-801) prevented the progressive development of seizures but did not block previously induced seizures. "

Related Drugs and Biologics

1. Styrene (Styrol)
2. Dentifrices (Dentifrice)
3. Triclosan (pHisoHex)
4. Edetic Acid (EDTA)
5. Zinostatin
6. 3- (2- carboxypiperazin- 4- yl)propyl- 1- phosphonic acid (CPP)
7. methoxyethylene-maleic anhydride copolymer
8. Ethyl Ether (Ether)
9. Silicon Dioxide (Sand)
10. Sodium Fluoride (Ossin)

Related Therapies and Procedures

1. Intra-Arterial Infusions
2. Solid-State Lasers
3. Drug Therapy (Chemotherapy)
4. Intra-Arterial Injections
5. Injections