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S-(2,4-dinitrophenyl)glutathione

Also Known As:

Dnp-SG; GS-DNP; GSH-S-DNP

Networked: 9 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Glutathione: 14524
      - S-(2,4-dinitrophenyl)glutathione: 9

Experts

1.	Mottino, Aldo D: 2 articles (08/2006 - 06/2002)
2.	Gerk, Phillip M: 1 article (05/2011)
3.	Vaidya, Soniya S: 1 article (05/2011)
4.	Walsh, Scott W: 1 article (05/2011)
5.	Mori, Nobuhiro: 1 article (06/2010)
6.	Murakami, Teruo: 1 article (06/2010)
7.	Yokooji, Tomoharu: 1 article (06/2010)
8.	Boyer, James L: 1 article (08/2006)
9.	Cai, Shi-Ying: 1 article (08/2006)
10.	Catania, Viviana A: 1 article (08/2006)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 05/01/2011 - "Cultured villous tissue was monitored up to 48 h to study the effect of time in culture on biochemical parameters, formation and efflux of DNP-SG in the absence or presence of ATPase inhibitor sodium orthovanadate and the protein expression of ABC transporters - multidrug resistance associated protein 2 (MRP2), P-glycoprotein (P-gp), breast cancer resistance protein (BCRP), and enzyme glutathione-S-transferase isoform P1-1 (GSTP1-1). "
2.	Cholestasis 08/01/2006 - "In conclusion, increased renal tubular conversion of CDNB to DNP-SG followed by subsequent Mrp2-mediated secretion into urine partially compensates for altered liver function in experimental obstructive cholestasis." 06/01/2002 - "Pretreatment with DBcAMP partially protected against maximal E(2)17G cholestasis and the endocytic retrieval and decreased function of Mrp2 at 20 minutes and significantly accelerated the exocytic insertion of Mrp2 into the canalicular membrane and the recovery of bile flow and biliary excretion of DNP-SG. "
3.	Neoplasms (Cancer) 09/01/1998 - "Since different sensitivities to antitumor electrophiles are shown by different cell types, the ability of several human cancer cell lines to produce and export S-(2,4-dinitrophenyl)-glutathione (DNP-SG) conjugate through the GS-X pump, using whole cells and inside-out membrane vesicle preparations, is investigated. "
4.	Infections 04/01/2005 - "After 72 h infection, we evaluated the protein expression and localization in the liver and the transport activity of [(3)H]E(2)17ssG and [(3)H]DNP-SG by preparing canalicular membrane vesicles (CMVs). "
5.	Hyperbilirubinemia 06/25/2010 - "The effect of hyperbilirubinemia on the function of tissue efflux transporters such as multidrug resistance-associated proteins (Mrps) and organic anion transporting polypeptides (Oatps) was examined by measuring tissue accumulation of 2,4-dinitrophenyl-S-glutathione (DNP-SG) after intravenous administration of 1-chloro-2,4-dinitrobenzene (CDNB), a precursor of DNP-SG, in rats. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Member 1 Subfamily B ATP Binding Cassette Transporter
3.	Protein Isoforms (Isoforms)
4.	ATP-Binding Cassette Transporters (ABC Transporters)
5.	Vanadates (Orthovanadate)
6.	Sodium
7.	Glutathione Transferase (Glutathione S-Transferase)
8.	Enzymes
9.	Adenosine Triphosphatases (ATPase)
10.	Multidrug Resistance-Associated Protein 2

Related Therapies and Procedures

1.	Intravenous Administration