roemerine

from root tubers of Stephania kwangsiensis H.S. Lo; RN given refers to (R)-isomer; synonym aporeine refers to (S)-isomer; structure in Merck Index, 9th ed, #779

Also Known As:

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Cui, Wei-Guo: 1 article (01/2017)
2.	Gui, Shi-Liang: 1 article (01/2017)
3.	Li, Wei: 1 article (01/2017)
4.	Ma, Hong-Bin: 1 article (01/2017)
5.	Tian, Zhong-Shi: 1 article (01/2017)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2017 - "We detected the effects of roemerine on the proliferation, apoptosis and migration of PCa cells DU145, LNCaP, PC-3 and 22RV1, screened out the sensitive cell line and constructed a tumor-bearing model in mice for verification of the antitumor efficacy of roemerine in vivo. " 01/01/2017 - "The average tumor weight was less in the roemerine intervention group (［1.99±0.95］ g) than in the control (［2.95±1.04］ g), the least in the high-dose roemerine (30 mg/kg) plus paclitaxel intervention group (［0.90±0.16］ g). " 01/01/2017 - "Pathological staining showed a lower degree of malignancy and metastasis in both the roemerine and the roemerine + paclitaxel intervention group than in the control, as well as a lower degree of visceral injury in the roemerine and roemerine + paclitaxel groups than in the paclitaxel group. "
2.	Prostatic Neoplasms (Prostate Cancer) 01/01/2017 - "[Anti-prostate cancer effect of roemerine: An experimental study]." 01/01/2017 - "To investigate the anti-prostate cancer (PCa) effect of roemerine in vitro and in vivo in the mouse model of PCa. "
3.	Pneumonia (Pneumonitis) 03/01/1989 - "However, only (+)-actinodaphnine (1) and roemerine methine (26) showed weak effects against two G(-) bacteria (Escherichia coli and Klebsiella pneumonia) (MIC = 300 micrograms/ml). "
4.	Neoplasm Metastasis (Metastasis) 01/01/2017 - "Pathological staining showed a lower degree of malignancy and metastasis in both the roemerine and the roemerine + paclitaxel intervention group than in the control, as well as a lower degree of visceral injury in the roemerine and roemerine + paclitaxel groups than in the paclitaxel group. "

Related Drugs and Biologics

1.	Paclitaxel (Taxol)