aristeromycin

RN given refers to (1R-(1alpha,2alpha,3beta,5alpha)-isomer

Also Known As:

aristeromycin, (1alpha,2alpha,3beta,5beta)-(+-)-isomer; aristeromycin, (1alpha,2beta,3beta,5beta)-(+-)-isomer; carbocyclic adenosine; cycloadenosine

Networked: 9 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Adenosine: 12431
        aristeromycin: 9
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Adenosine: 12431
      - aristeromycin: 9
  - Ribonucleosides: 49
    - Adenosine: 12431
      - aristeromycin: 9

Experts

1.	Albulescu, Irina C: 1 article (01/2020)
2.	Jang, Min Hwan: 1 article (01/2020)
3.	Jarhad, Dnyandev B: 1 article (01/2020)
4.	Jeong, Lak Shin: 1 article (01/2020)
5.	Kim, Gyudong: 1 article (01/2020)
6.	Kovacikova, Kristina: 1 article (01/2020)
7.	Lee, Hyuk Woo: 1 article (01/2020)
8.	Morren, Bas M: 1 article (01/2020)
9.	Shin, Young Sup: 1 article (01/2020)
10.	Snijder, Eric J: 1 article (01/2020)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 10/05/2017 - "Aristeromycin and DZNeP cause growth inhibition of prostate cancer via induction of mir-26a." 10/05/2017 - "In the present study, a differential cytotoxicity screen of hormone-resistant prostate cancer LNCaP-hr cells and the parental LNCaP-FGC cells against normal MRC5 fibroblast cells, identified a small molecule compound, Aristeromycin (a derivative of 3-deazaneplanocin A (DZNeP)). "
2.	Vesicular Stomatitis 04/01/1989 - "For a series of acyclic and carbocyclic adenosine analogues, a close correlation was found between their inhibitory effect on murine L929 cell S-adenosylhomocysteine (AdoHcy) hydrolase and their inhibitory effects on the replication of vaccinia virus and vesicular stomatitis virus (r: 0.993 and 0.988, respectively). "
3.	Teratocarcinoma 03/05/1992 - "F9 teratocarcinoma cells, stably transfected with two collagen (IV) promoter-enhancer-CAT constructs and treated with 10 microM 3-deazaadenosine, 3-deaza-(+-)-aristeromycin or 3-deazaneplanocin, showed a strong induction of CAT activities without affecting differentiation. "
4.	Necrosis 12/01/1996 - "The effects of 3-deazaadenosine (DZA), 3-deaza(+/-)-aristeromycin (DZAri) and 3-deazaneplanocin (DZNep) on tumour necrosis factor-alpha (TNF-alpha) production were examined in the mouse macrophage cell line, RAW264.7, stimulated with lipopolysaccharide (LPS). "
5.	Experimental Melanoma 04/01/1988 - "In murine B16 melanoma cells, periodate-oxidised adenosine, 3-deaza-adenosine and 3-deaza-(+/-)aristeromycin reduced the intracellular ratio of S-adenosylmethionine/S-adenosylhomocysteine approximately 17-, 13- and 32-fold, respectively. "

Related Drugs and Biologics

1.	3-deazaneplanocin
2.	Hormones (Hormone)
3.	3-deazaadenosine
4.	S-Adenosylhomocysteine
5.	Antiviral Agents (Antivirals)
6.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
7.	S-Adenosylmethionine (Ademetionine)
8.	Lipopolysaccharides
9.	Hydrolases
10.	Collagen