proenkephalin

05/01/2011 - "In the present study, we investigated the antinociceptive effect of herpes simplex virus type 1 (HSV-1) amplicon vector-mediated human proenkephalin (hPPE) on chronic constriction injury (CCI)-induced neuropathic pain in rats. "
04/01/2012 - "We investigated the antinociceptive effect of microinjection of HSV-1 amplicon vector-mediated human proenkephalin (hPPE) into the ventral periaqueductal grey (PAG) on neuropathic pain in rats. "
04/01/2012 - "Microinjection of HSV-1 amplicon vector-mediated human proenkephalin into the periaqueductal grey attenuates neuropathic pain in rats."
05/01/2011 - "Intrathecal herpes simplex virus type 1 amplicon vector-mediated human proenkephalin reduces chronic constriction injury-induced neuropathic pain in rats."
03/01/2003 - "We examined the pharmacologic characteristics of herpes simplex virus (HSV) vector-mediated expression of proenkephalin in the dorsal root ganglion in a rodent model of neuropathic pain. "

11/15/2023 - "The role of Proenkephalin A 119-159 in the detection of acute kidney injury after open thoracoabdominal aortic repair."
09/01/2020 - "Proenkephalin A 119-159 May Predict Post-operative Acute Kidney Injury and in Hospital Mortality Following Open or Endovascular Thoraco-abdominal Aortic Repair."
01/01/2015 - "Proenkephalin predicts acute kidney injury in cardiac surgery patients."
10/09/2023 - "Recently, proenkephalin A (PENK A) has been shown to reflect glomerular dysfunction and to predict new-onset acute kidney injury and heart failure. "
10/01/2018 - "Proenkephalin for the early detection of acute kidney injury in hospitalized patients with chronic kidney disease."

09/03/2009 - "The functional significance of proenkephalin systems in processing pain remains an open question and indeed is puzzling. "
06/15/2006 - "Vector-mediated reduction in pain-related behavior was higher in magnitude and longer in duration after inoculation of the GAD-expressing vector than that achieved by the inoculation of the proenkephalin-expressing vector. "
03/01/2004 - "Thus, in polyarthritic rat, a model of chronic inflammatory pain, we demonstrated that herpes simplex virus vector mediated overexpression of proenkephalin A in primary sensory neurons at the lumbar level elicited both antihyperalgesic and anti-inflammatory activities. "
10/01/2003 - "Interestingly, overexpression of proenkephalin A in primary sensory neurones induced antinociceptive effects in persistent pain of inflammatory, neuropathic and cancerous origins. "
01/01/2017 - "This study aimed to investigate the use of human bone marrow mesenchymal stem cells (hBMSCs) genetically engineered with the human proenkephalin (hPPE) gene to treat bone cancer pain (BCP) in a rat model. "

01/01/2020 - "Proenkephalin Compared to Conventional Methods to Assess Kidney Function in Critically Ill Sepsis Patients."
12/01/2015 - "Diagnostic and short-term prognostic utility of plasma pro-enkephalin (pro-ENK) for acute kidney injury in patients admitted with sepsis in the emergency department."
12/04/2022 - "Bio-adrenomedullin (Bio-ADM) and Proenkephalin (PenKid) seem to have a key role in the development of organ dysfunctions induced by sepsis and, therefore, could help in the risk stratification of patients with sepsis at ED admission. "
12/04/2022 - "30 Days Mortality Prognostic Value of POCT Bio-Adrenomedullin and Proenkephalin in Patients with Sepsis in the Emergency Department."
09/01/2017 - "Proenkephalin, Neutrophil Gelatinase-Associated Lipocalin, and Estimated Glomerular Filtration Rates in Patients With Sepsis."

10/31/2022 - "Proenkephalin A 119-159 (penKid) has been suggested as a promising marker of kidney function in the context of AKI, but has not yet been evaluated for RRT liberation in critically ill patients with AKI. "
01/01/2020 - "Proenkephalin Compared to Conventional Methods to Assess Kidney Function in Critically Ill Sepsis Patients."
01/01/2023 - "Proenkephalin A as a marker for glomerular filtration rate in critically ill children: validation against gold standard iohexol GFR measurements."
10/31/2022 - "Proenkephalin A 119-159 predicts early and successful liberation from renal replacement therapy in critically ill patients with acute kidney injury: a post hoc analysis of the ELAIN trial."
10/01/2023 - "Recent evidence suggests an association of plasma Proenkephalin A 119-159 (penKid) with early and successful liberation from continuous renal replacement therapy (CRRT) in critically ill patients with acute kidney injury. "