2,2',3',4,4',5-hexachlorobiphenyl

Also Known As:

2,3,4,2',4',5'-hexachlorobiphenyl; PCB 138

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Biphenyl Compounds: 7
        Polychlorinated Biphenyls: 1778
        2,2',3',4,4',5-hexachlorobiphenyl: 8
  - Halogenated Hydrocarbons: 42
    - Chlorinated Hydrocarbons: 240
      - Polychlorinated Biphenyls: 1778
        2,2',3',4,4',5-hexachlorobiphenyl: 8
- Dioxins and Dioxin-like Compounds: 5
  - Polychlorinated Biphenyls: 1778
    - 2,2',3',4,4',5-hexachlorobiphenyl: 8

Experts

1.	Beckers, Albert: 1 article (01/2020)
2.	Charlier, Corinne: 1 article (01/2020)
3.	Dufour, Patrice: 1 article (01/2020)
4.	Petrossians, Patrick: 1 article (01/2020)
5.	Pirard, Catherine: 1 article (01/2020)
6.	Kelly, Barry C: 1 article (01/2018)
7.	Wang, Qian: 1 article (01/2018)
8.	Deoraj, Alok: 1 article (12/2017)
9.	Felty, Quentin: 1 article (12/2017)
10.	Morgan, Marisa: 1 article (12/2017)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 12/05/2017 - "Our results suggest a link between environmental exposures to PCB 138 and breast cancer. " 01/01/2023 - "(iii) Five polychlorinated biphenyls (PCB 99, PCB 105, PCB 118, PCB 138, and PCB 183) can increase the risk of breast cancer. " 02/15/2001 - "The multivariate relative risk of breast cancer for women in the highest quintile of exposure as compared with women in the lowest quintile was 0.82 for DDE (95% confidence interval [CI]: 0.49-1.37) and 0.84 for total PCBs (95% CI: 0.47-1.52), 0.69 for PCB 118 (95% CI: 0.39-1.22), 0.87 for PCB 138 (95% CI: 0.50-1.50), 0.83 for PCB 153 (95% CI: 0.47-1.48), and 0.98 for PCB 180 (95% CI: 0.55-1.75). " 01/01/2002 - "Using human breast cancer cell lines MCF-7 and MDA-MB-231, the effect on BRCA1 expression of chemicals belonging to different classes of organochlorine chemicals (the pesticide toxaphene, 2,3,7,8-tetrachlorodibenzo-p-dioxin, and three polychlorinated biphenyls [PCB#138, PCB#153 and PCB#180]) was measured by a reporter gene construct carrying 267 bp of the BRCA1 promoter. "
2.	Urologic Diseases (Urinary Tract Disease) 07/01/2011 - "A distinct difference was observed in renal and urological diseases, organisimal injury and abnormalities, dental disease, ophthalmic disease, and psychological disorders, which are only revealed by PCB 138 exposure, but not in PCB 153. "
3.	Stomatognathic Diseases (Dental Disease) 07/01/2011 - "A distinct difference was observed in renal and urological diseases, organisimal injury and abnormalities, dental disease, ophthalmic disease, and psychological disorders, which are only revealed by PCB 138 exposure, but not in PCB 153. "
4.	Leiomyoma (Uterine Fibroids) 05/01/2015 - "In analyses excluding women diagnosed with endometriosis, a number of polychlorinated biphenyls (PCBs) measured in omental fat were associated with fibroids (PCB 99: 1.64 (1.08, 2.49); PCB 138: 1.64 (1.03, 2.59); PCB 146: 1.54 (1.01, 2.37); PCB 153: 1.88 (1.12, 3.13); PCB 196: 1.60 (1.02, 2.51); PCB 206: 1.52 (1.01, 2.29)). "
5.	Hypothyroidism 01/01/2020 - "The WQS index was statistically significantly associated with an increased odds of hypothyroidism (odds ratio (OR) = 98.1; 95% CI: 5.51-1747) with the highest weights attributed to PCB 138 (w = 0.210), 3-OH-CB 180 (w = 0.197), 4-OH-CB 146 (w = 0.188), 4',4-DDE (w = 0.156) while there were no evidence of a relation with increased odds of hyperthyroidism. "

Related Drugs and Biologics

1.	2,4,5,2',4',5'-hexachlorobiphenyl
2.	Polychlorinated Biphenyls (PCBs)
3.	Dichlorodiphenyl Dichloroethylene (DDE)
4.	PCB 180
5.	2,3',4,4',5-pentachlorobiphenyl
6.	Toxaphene
7.	Pesticides
8.	Dichlorodiphenyldichloroethane (DDD)
9.	Polychlorinated Dibenzodioxins (TCDD)
10.	2,3,3',4,4'-pentachlorobiphenyl