2,3-bis(3'-hydroxybenzyl)butyrolactone (enterolactone)

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84 relevant articles (8 outcomes, 21 trials/studies) found for this Bio-Agent

Description: lignan isolated from urine of humans & other mammals; RN given refers to cpd without isomeric designation; structure given in second source

Also Known As:

enterolactone; 2,3-BHBB; 2,3-bis(3'-hydroxybenzyl)butyrolactone, (trans)-(+-)-isomer; 2,3-bis(3'-hydroxybenzyl)butyrolactone, (trans)-isomer; 3,4-bis((3-hydroxyphenyl)methyl)dihydro-2-(3H)-furanone; BHMDF; HPMF; trans-2,3-bis(3-hydroxybenzyl)-gamma-butyrolactone; 2(3H)-Furanone, dihydro-3,4-bis((3-hydroxyphenyl)methyl)-

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 40

Hydrocarbons: 382

Cyclic Hydrocarbons: 2

Aromatic Hydrocarbons: 115

Benzene Derivatives: 9

Benzyl Compounds: 1

Lignans: 209

2,3-bis(3'-hydroxybenzyl)butyrolactone: 84

Lactones: 133

4-Butyrolactone: 63

2,3-bis(3'-hydroxybenzyl)butyrolactone: 84

Heterocyclic Compounds: 23

1-Ring Heterocyclic Compounds

Furans: 33

4-Butyrolactone: 63

2,3-bis(3'-hydroxybenzyl)butyrolactone: 84

Experts

1.	Adlercreutz, Herman: 8 articles (11/2006 - 05/2002)
2.	Adlercreutz, H: 4 articles (08/2008 - 04/2001)
3.	Hallmans, Göran: 4 articles (11/2006 - 05/2002)
4.	Saarinen, Niina M: 3 articles (01/2007 - 08/2002)
5.	Stattin, Pär: 3 articles (11/2006 - 05/2002)
6.	Virtanen, Mikko J: 3 articles (04/2006 - 11/2003)
7.	Virtamo, Jarmo: 3 articles (04/2006 - 11/2003)
8.	Kilkkinen, Annamari: 3 articles (04/2006 - 11/2003)
9.	Kaaks, Rudolf: 2 articles (11/2006 - 12/2004)
10.	Lenner, Per: 2 articles (11/2006 - 08/2002)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 07/05/2004 - "We conducted a case-control study of breast cancer and serum levels of the main human lignan, enterolactone, nested within a prospective cohort study, the New York University Women's Health Study" 01/10/2004 - "Enterolactone concentrations were measured by time-resolved fluoroimmunoassay in serum collected at 4 independent cross-sectional population surveys from 206 women with breast cancer diagnosed during follow-up (mean 8.0 years) and from 215 controls frequency-matched to cases by study cohort, 5-year age group and study area" 01/01/2003 - "Three studies measured enterolactone (lignan): two case control studies reported a preventive effect on breast cancer risk, but the only prospective study did not " 04/01/2001 - "The purpose of this study was to examine the association between serum enterolactone and risk of breast cancer in Finnish women" 11/01/1986 - "In an earlier study the lowest excretion of enterolactone (1,040 nmol/24 h) was found in a group of postmenopausal apparently healthy breast cancer patients living in Boston" Get all the results and reference details, order at left...
2.	Prostatic Neoplasms (Prostate Cancer) 05/01/2002 - "No support for the hypothesis that high circulating enterolactone is protective against prostate cancer was found." 09/01/2007 - "Our findings encourage further studies of enterolactone as a promising chemopreventive agent against prostate cancer." 09/01/2007 - "In this study, we report that enterolactone selectively suppresses the growth of LNCaP prostate cancer cells by triggering apoptosis" 07/01/2005 - "One study assessed enterolactone concentrations in three different countries and showed no reduction in prostate cancer occurrence" 05/01/2002 - "Odds ratios of prostate cancer risk estimated by conditional logistic regression for increasing concentrations of enterolactone in quartiles in the full study group were 1.00 (referent), 1.21 (95% confidence interval [CI] = 0.96-1.52), 1.16 (95% CI = 0.91-1.47) and 1.08 (95% CI = 0.83-1.39)" Get all the results and reference details, order at left...
3.	Neoplasms (Cancer) 12/18/1999 - "BACKGROUND: The lignan enterolactone, produced by the intestinal microflora from dietary precursors, has been implicated in protection against cancer" 08/01/2008 - "CONCLUSIONS: Although the estimated ICC for blood samples was moderate, it indicates that enterolactone levels of both fasting and non-fasting blood samples should be useful in future projects within the Malmö Diet and Cancer cohort." 08/01/2008 - "Variation in fasting and non-fasting serum enterolactone concentrations in women of the Malmö Diet and Cancer cohort." 05/12/2003 - "BACKGROUND: Enterolactone is a plant-derived compound that has been associated with a reduced risk of acute coronary events and cancer" 08/01/2002 - "Both intake of whole grain and higher levels of serum enterolactone have been related to reduced risk for CHD and some cancers" Get all the results and reference details, order at left...
4.	Colonic Neoplasms (Colon Cancer) 05/01/2005 - "Enterolactone induces apoptosis and inhibits growth of Colo 201 human colon cancer cells both in vitro and in vivo." 03/01/2005 - "The cancer preventive mechanisms of 2 prominent lignan metabolites (enterolactone and enterodiol) were further studied in human colonic cancer SW480 cells" 12/01/1994 - "A strong research effort has been devoted in recent years to the mammalian lignans enterolactone and enterodiol because of their claimed protective effects against breast and colon cancer" Get all the results and reference details, order at left...
5.	DNA Damage 06/01/2000 - "In contrast, enterolactone, dihydrogenistein and formononetin reduced endogenous oxidative DNA damage at 100 microM" 11/01/2007 - "The flaxseed lignan secoisolariciresinol diglucoside (SDG) and mammalian lignans enterodiol (ED) and enterolactone (EL) were previously shown to be effective antioxidants against DNA damage and lipid peroxidation" Get all the results and reference details, order at left...
29 Diseases and 84 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Lignans
2.	2,3-bis(3'-hydroxybenzyl)butane-1,4-diol (enterodiol)
3.	Genistein
4.	Phytoestrogens (Phytoestrogen)
5.	Hormones
6.	matairesinol
7.	secoisolariciresinol
8.	Antioxidants
9.	secoisolariciresinol diglucoside
10.	equol
41 Drugs and Important Bio-Agents and 66 more articles analyzed in the Research Interface, order at left...

Related Therapies and Procedures

1.	Vegetarian Diet (Vegetarianism)
1 Therapies and Procedures and 1 more articles analyzed in the Research Interface, order at left...

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