thymidine glycol

RN given refers to cpd without isomeric designation

Also Known As:

5,6-dihydro-5,6-dihydroxythymidine; 5,6-dihydroxy-5,6-dihydrothymidine; glycolthymidine; thymidine glycol, (5R*,6S*)-isomer; thymidine glycol, (5R,6R)-isomer; thymidine glycol, (5R,6S)-isomer; thymidine glycol, (5S,6R)-isomer; thymidine glycol, (5S,6S)-isomer; thymidine glycol, (cis)-isomer; thymidine glycol, (trans)-isomer

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Date, Fumiko: 1 article (02/2014)
2.	Mori, Shiro: 1 article (02/2014)
3.	Ono, Masao: 1 article (02/2014)
4.	Saito, Keiichi: 1 article (02/2014)
5.	Heintz, B: 1 article (01/2000)
6.	Kocher, K: 1 article (01/2000)
7.	Makropoulos, W: 1 article (01/2000)
8.	Mertens, P R: 1 article (01/2000)
9.	Schwarz, E R: 1 article (01/2000)
10.	Stefanidis, I: 1 article (01/2000)

Related Diseases

1.	Body Weight (Weight, Body) 04/01/1988 - "On a body weight basis, mice excrete 18 times more thymine glycol plus thymidine glycol than do humans, and monkeys excrete 4 times more thymine glycol plus thymidine glycol than do humans. " 09/01/1984 - "Rats, which have a higher specific metabolic rate and a shorter life span, excrete about 15 times more thymine glycol plus thymidine glycol per kg of body weight than do humans. "
2.	Sialadenitis 02/01/2014 - "Herein, we examined the effects of EGCG administration to MRL/MpJ-lpr/lpr (MRL-Fas(lpr)) mice on disease severity of autoimmune sialadenitis and protein expression levels of 11 sialadenitis-related molecules - heme oxygenase-1 (HO-1) (antioxidant); thymidine glycol (marker of DNA damage); gp91phox/NADPH oxidase 2 (prooxidant); single-stranded DNA (ssDNA) and cleaved caspase 3 (apoptotic cell markers); p53 and Bax (proapoptotic molecules); Bcl-2 (antiapoptotic molecule); SSA/Ro, SSB/La, and Ifi202 (autoantigens). "
3.	Ischemia 01/01/2000 - "An increased excretion of thymidine glycol is seen after kidney transplantation and is explained by the ischemia-reperfusion induced oxidative DNA damage in the kidney. "

Related Drugs and Biologics

1.	thymine glycol
2.	Caspase 3 (Caspase-3)
3.	Heme Oxygenase-1
4.	Proteins (Proteins, Gene)
5.	Single-Stranded DNA (DNA, Single Stranded)
6.	Autoantigens
7.	Antioxidants
8.	NADPH Oxidase 2

Related Therapies and Procedures

1.	Kidney Transplantation