Clostridium perfringens delta-toxin (CPDT)

03/01/2021 - "Pain was more pronounced in patients treated with cPDT in comparison with TCA (MD -1.71 95% CI: -3.02 to -0.41, two studies, I2  = 55%, P = 0.01). "
06/01/2020 - "We perform a prospective, randomized, single-blind, two-center trial (The 3P-Trial) to assess the pain reduction effect of LT-C versus vehicle in subjects with AK undergoing cPDT. "
11/01/2020 - "The main disadvantage of cPDT is the pain experienced by the patients during illumination. "
06/01/2020 - "The main outcome was the patient-assessed evaluation of pain score during and just after the conclusion of cPDT session (mean of the two values) using a 10-point visual analog scale (VAS). "
06/01/2020 - "There are no data regarding its pain reducing effect during cPDT. "

06/01/2020 - "Conventional photodynamic therapy (cPDT) is considered a very effective treatment of actinic keratosis (AK) lesions. "
04/01/2018 - "Several trials demonstrate that DLPDT achieves similar response rates with conventional PDT (CPDT) in the treatment of non-hyperkeratotic actinic keratoses (AKs) in a nearly painless way. "
11/01/2020 - "Conventional photodynamic therapy (cPDT) using red light is considered one of the most effective therapy option for the treatment of actinic keratosis (AK). "
06/01/2020 - "Efficacy of lidocaine 7 %, tetracaine 7 % self-occlusive cream in reducing MAL-cPDT-associated pain in subjects with actinic keratosis: A randomized, single-blind, vehicle-controlled trial (The "3P-Trial")."

01/01/2017 - "The purpose of this study is to investigate the protective effects and potential mechanism of CPDT in diabetic cardiomyopathy. "
01/01/2017 - "Therefore, miR-503 is involved in the protective effect of CPDT in diabetic cardiomyopathy via Nrf2/ARE signaling pathway; miR-503 and Nrf2 may be a promising therapeutic target for the management of diabetic cardiomyopathy."
01/01/2017 - "Furthermore, compared with diabetic cardiomyopathy rats, these above parameters show the opposite change in CPDT treatment rats. "
01/01/2017 - "miR-503 Is Involved in the Protective Effect of Phase II Enzyme Inducer (CPDT) in Diabetic Cardiomyopathy via Nrf2/ARE Signaling Pathway."

04/01/1998 - "Antibody results were similar to those observed in a Swedish field trial that demonstrated CPDT to be 85% effective in preventing clinical pertussis."
04/01/1998 - "Safety, immunogenicity and lot consistency of five-component pertussis combination vaccine (CPDT-IPV//PRP-T) in infants were compared to that of whole cell pertussis combination vaccine (DPT-IPV//PRP-T), as were separate and combined injections of CPDT-IPV and PRP-T. "

02/01/1993 - "Targeting of GM2-bearing tumor cells with the cytolytic Clostridium perfringens delta toxin."
01/01/2022 - "Although numerous papers related to cancer PDT (CPDT) have been published, no bibliometric studies have been conducted to summarize the research landscape, and highlight the research trends and hotspots in this field. "
12/01/2020 - "Previous studies have shown that 2-(4-fluorophenyloamino)-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole (FPDT) and 2-(3-chlorophenyloamino)-5-(2,4-dihydroxyphenyl)-1,3,4-thiadiazole (CPDT) diminished viability of cancer cell lines of different origin. "
12/31/2023 - "Combination therapy merges chemical photodynamic therapy (CPDT) to improve cancer treatment. "