1-naphthol (alpha-naphthol)

RN given refers to parent cpd

Also Known As:

alpha-naphthol; 1-hydroxynaphthalene; 1-naphthol, 1-(14)C-labeled; 1-naphthol, 2-(13)C-labeled; 1-naphthol, ion(1+); 1-naphthol, lithium salt; 1-naphthol, potassium salt; 1-naphthol, sodium salt

Networked: 50 relevant articles (1 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthols: 64
        1-naphthol: 50
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthols: 64
      - 1-naphthol: 50

Experts

1.	Munson-McGee, Stuart H: 3 articles (08/2022 - 01/2022)
2.	Niemann, Danielle: 3 articles (08/2022 - 01/2022)
3.	Rahman, Humairat H: 3 articles (08/2022 - 01/2022)
4.	Swain, Jitendriya: 2 articles (07/2016 - 07/2015)
5.	Chang, Li: 1 article (11/2022)
6.	Ding, Jie: 1 article (11/2022)
7.	Jia, Teng: 1 article (11/2022)
8.	Wang, Fang: 1 article (11/2022)
9.	Wang, Yu: 1 article (11/2022)
10.	Wang, Yuying: 1 article (11/2022)

Related Diseases

1.	Metabolic Diseases (Metabolic Disease) 01/01/2023 - "It also demonstrated a great promise in alleviating non-alcoholic steatohepatitis (NASH) and liver fibrosis, attenuated alpha-naphthol isothiocyanate (ANIT)-induced cholestatic liver injury, and controlled blood glucose levels, making it a key player in the therapy of metabolic diseases. "
2.	Liver Cirrhosis (Hepatic Cirrhosis) 01/01/2023 - "It also demonstrated a great promise in alleviating non-alcoholic steatohepatitis (NASH) and liver fibrosis, attenuated alpha-naphthol isothiocyanate (ANIT)-induced cholestatic liver injury, and controlled blood glucose levels, making it a key player in the therapy of metabolic diseases. "
3.	Alcoholic Fatty Liver 01/01/2023 - "It also demonstrated a great promise in alleviating non-alcoholic steatohepatitis (NASH) and liver fibrosis, attenuated alpha-naphthol isothiocyanate (ANIT)-induced cholestatic liver injury, and controlled blood glucose levels, making it a key player in the therapy of metabolic diseases. "
4.	Neoplasms (Cancer) 01/01/2020 - "The synthesized 1-naphthol compounds showed good antitumor activity in vitro, and further studies indicated that compound 3bl induced tumor cell apoptosis." 01/01/1983 - "The study indicates that the non-specific alpha-naphthol acetate esterase activity of monocytes derived from patients with cancer and control group did not show a marked difference. " 03/01/1983 - "The oxidative metabolism of benzo(a)pyrene and the conjugative metabolism of 1-naphthol by explant cultures of normal human colon and colonic tumor tissue, obtained at surgery, have been studied. " 01/01/1983 - "In 22 patients with cancer of the alimentary tract the activities of acid phosphatase and non-specific alpha-naphthol acetate esterase in monocytes were tested. " 01/01/1983 - "Acid phosphatase and non-specific alpha-naphthol acetate esterase activities of monocytes in patients with cancer of the digestive tract during surgical treatment."
5.	Stroke (Strokes) 08/01/2023 - "Four species of urinary PAHs, including the third quantiles of 1-hydroxynaphthalene [odds ratio (OR): 2.327, 95% confidence interval (CI): 0.961-5.632], 2-hydroxynaphthalene [OR: 2.449, 95% CI: 1.067-5.622], and 3-hydroxyfluorene [OR: 2.289, 95% CI: 1.077-4.861] and the second quantiles of 3-hydroxyfluorene [OR: 2.201, 95% CI: 1.115, 4.346] and 1-hydroxypyrene [OR: 2.066, 95% CI: 1.037, 4.114], showed a positive correlation with increased odds of stroke. " 09/01/2015 - "They tended to be aged 40-60, female, Mexican American, other Hispanic, education less than high school, or poverty income ratio 5+. People with higher levels of butyl paraben, ethyl paraben, methyl paraben, 1-hydroxynaphthalene, 2-hydroxynaphthalene, or 9-hydroxyfluorene (but not heavy metals, arsenic, phenols, phthalates, pesticides, or phytoestrogens) or historical diabetes, asthma, arthritis, stroke, thyroid disorder, chronic bronchitis, sleep complaint/disorder, or trouble seeing needed more emotional support. " 08/01/2023 - "This study aimed to assess different arsenic species, including total arsenic; two types of organic arsenic, i.e., arsenobetaine and arsenocholine; four types of inorganic arsenic, i.e., arsenic acid, arsenous acid, dimethylarsinic acid (DMA), and monomethylarsonic acid (MMA); six types of urinary polycyclic aromatic hydrocarbon (PAH) compounds, i.e., 1-hydroxynaphthalene, 1-hydroxyphenanthrene, 1-hydroxypyrene, 2-hydroxynaphthalene, 2-hydroxyfluorene, and 3-hydroxyfluorene; and fourteen types of metals from urine specimen, i.e., manganese, cadmium, lead, mercury, barium, cobalt, strontium, molybdenum, cesium, thallium, antimony, tin, tungsten, and uranium and their association with those who reported having been told they had had a stroke by a medical professional. "

Related Drugs and Biologics

1.	Blood Glucose (Blood Sugar)
2.	isothiocyanic acid
3.	1-hydroxypyrene
4.	2-naphthol
5.	1-hydroxyphenanthrene
6.	2-hydroxyfluorene
7.	Acetylesterase
8.	fluoren-9-ol
9.	naphthalene
10.	Mercury

Related Therapies and Procedures

1.	Therapeutics
2.	Ligation