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1- nitro- 9- (2- dihydroxyethylaminoethylamino)acridine (C 835)

structure given in first source

Also Known As:

C 835; C-835; Ethanol, 2,2'-((2-((1-nitro-9-acridinyl)amino)ethyl)imino)bis-

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Acridines: 325
      - Aminoacridines: 3
        Aminacrine: 77
        1-nitro-9-(2-dihydroxyethylaminoethylamino)acridine: 4

Experts

1.	Ito, Akihiko: 1 article (09/2022)
2.	Kanemura, Hiroaki: 1 article (09/2022)
3.	Kimura, Masatomo: 1 article (09/2022)
4.	Matsuki, Mitsuru: 1 article (09/2022)
5.	Matsumura, Noriomi: 1 article (09/2022)
6.	Mitani, Seiichiro: 1 article (09/2022)
7.	Nakagawa, Kazuhiko: 1 article (09/2022)
8.	Otani, Tomoyuki: 1 article (09/2022)
9.	Satou, Takao: 1 article (09/2022)
10.	Takeda, Masayuki: 1 article (09/2022)

Related Diseases

1.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 12/13/2016 - "P2RX7 253 T/C, 835 G/A, and 1513 A/C loss-of-function polymorphisms were genotyped in a hospital-based study of 507 women with cervical squamous cell carcinoma (CSCC) and 1619 age-matched healthy control women. "
2.	Hypercalciuria 06/01/2022 - "We describe 23Na MRI and the successful use of recombinant human growth hormone (rhGH) and Fluconazole to improve growth (possibly confounded by puberty) and hypercalciuria in a now 12-year-old male with HHRH (novel homozygous SLC34A3 mutation, c.835_846 + 10del.T). "
3.	Neoplasms (Cancer) 09/01/2022 - "With the help of the next-generation sequencing results of the recurrent tumor, APC c.835 - 8A > G and TP53 c.524G > A (p.R175H) mutations were identified by direct sequencing in both the primary and the recurrent tumors, confirming the relationship between the two metachronous tumors."
4.	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 06/01/2018 - "c.835-5T>G Variant in SMN1 Gene Causes Transcript Exclusion of Exon 7 and Spinal Muscular Atrophy."

Related Drugs and Biologics

1.	Human Growth Hormone (Saizen)
2.	Fluconazole (Zonal)