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4-acetylaminofluorene

Also Known As:

4-AAF

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Related Diseases

1.	Carcinogenesis 02/01/1994 - "4-AAF is confirmed to be, at best, a very weak promoter of liver carcinogenesis, but appears to be an effective promoter of benign tumours."
2.	Chromosome Aberrations (Chromosome Abnormalities) 12/01/1994 - "A genetically engineered V79 cell line expressing rat CYP1A2 and another cell line expressing rat CYP1A2 as well as endogenous acetyltransferase activity, as well as CYP-deficient parental V79 cell lines, were used to assess the genotoxicity of the aromatic amines and amides 2-aminoanthracene, 2-aminofluorene, 2-acetylaminofluorene, 4-acetylaminofluorene and 2-amino-3-methylimidazo[4,5-f]quinoline, with chromosomal aberrations and sister chromatid exchanges as the end-points. "
3.	Carcinoma (Carcinomatosis) 02/01/1994 - "The analogue 4-acetylaminofluorene (4-AAF) was much less effective than 2-AAF as a promoter of large nodules and carcinomas, but promoted the outgrowth of medium-sized nodules (1 < 2.5 mm). "

Related Drugs and Biologics

1.	2-Acetylaminofluorene (2 Acetylaminofluorene)
2.	Cytochrome P-450 CYP1A2 (CYP1A2)
3.	Amines
4.	Amides
5.	Acetyltransferases
6.	quinoline
7.	2-aminofluorene
8.	2-anthramine