cyclohexylalanine

RN given refers to cpd without isomeric designation

Also Known As:

L-cyclohexylalanine; cyclohexylalanine hydrochloride; cyclohexylalanine, (+-)-isomer; cyclohexylalanine, (R)-isomer; cyclohexylalanine, (S)-isomer

Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Essential Amino Acids: 1152
    - Phenylalanine: 4090
      - cyclohexylalanine: 5
  - Cyclic Amino Acids: 3
    - Aromatic Amino Acids: 467
      - Phenylalanine: 4090
        cyclohexylalanine: 5

Experts

1.	Chung, Nga N: 2 articles (02/2012 - 01/2007)
2.	Schiller, Peter W: 2 articles (02/2012 - 01/2007)
3.	Ding, Jinguo: 1 article (02/2012)
4.	Lemieux, Carole: 1 article (02/2012)
5.	Ballet, Steven: 1 article (01/2007)
6.	Benyhe, Sándor: 1 article (01/2007)
7.	Borsodi, Anna: 1 article (01/2007)
8.	Ioja, Eniko: 1 article (01/2007)
9.	Martinek, Tamás: 1 article (01/2007)
10.	Péter, Antal: 1 article (01/2007)

Related Diseases

1.	Colitis 11/15/2003 - "We have compared the efficacy of an orally active human C5a receptor antagonist (AcPhe[Orn-Pro-D-cyclohexylalanine-Trp-Arg]), prednisolone, and infliximab against trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats. "
2.	Tics (Tic) 06/05/2003 - "The C-terminal Phe was replaced by Gly, cyclohexylalanine (Cha), Tyr, all four isomers of beta-methylphenylalanine (beta-MePhe), and l- and d-tetrahydroisoquinoline carboxylic acid (Tic), resulting in analogues 3-11. " 01/25/2007 - "The opioid peptide TIPP (H-Tyr-Tic-Phe-Phe-OH, Tic:1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid) was substituted with Dmt (2',6'-dimethyltyrosine) and a new unnatural amino acid, beta-MeCha (beta-methyl-cyclohexylalanine). " 02/01/2012 - "On the basis of evidence that opioid compounds with a mixed μ agonist/δ antagonist profile may produce an antinociceptive effect with low propensity to induce side effects, bifunctional opioid peptides containing the μ agonist H-Dmt-d-Arg-Phe-Lys-NH(2) ([Dmt(1) ]DALDA; Dmt = 2',6'-dimethyltyrosine) connected tail-to-tail via various α,ω-diaminoalkyl- or diaminocyclohexane linkers to the δ antagonists H-Tyr-TicΨ[CH(2) -NH]Cha-Phe-OH (TICP[Ψ]; Cha = cyclohexylalanine, Tic = 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid), H-Dmt-Tic-OH or H-Bcp-Tic-OH (Bcp = 4'-[N-((4'-phenyl)phenethyl)carboxamido]phenylalanine) were synthesized and pharmacologically characterized in vitro. "
3.	Arthus Reaction 12/01/2001 - "We now demonstrate in rats that oral administration of the C5a receptor antagonist AcPhe[Orn-Pro-D-Cyclohexylalanine-Trp-Arg] (AcF-[OPdChaWR]; 1 - 10 mg kg(-1) 30 min prior to immune-complex deposition) inhibits these inflammatory markers in the peritoneal Arthus reaction. "

Related Drugs and Biologics

1.	Anaphylatoxin C5a Receptor
2.	Sulfonic Acids
3.	Prednisolone (Predate)
4.	Infliximab (Remicade)
5.	Opioid Peptides (Opioid Peptide)
6.	Carboxylic Acids
7.	1,2,3,4-tetrahydroisoquinoline
8.	Phenylalanine (L-Phenylalanine)
9.	Antigen-Antibody Complex (Immune Complex)
10.	Opioid Analgesics (Opioids)

Related Therapies and Procedures

1.	Oral Administration