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apotransferrin

transferrin which is incompletely saturated with iron
Networked: 35 relevant articles (3 outcomes, 2 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Parkkinen, Jaakko: 4 articles (06/2004 - 06/2003)
2. von Bonsdorff, Leni: 3 articles (03/2004 - 06/2003)
3. Kondapi, Anand K: 2 articles (01/2013 - 01/2012)
4. Ahmed, Farhan: 2 articles (01/2013 - 01/2012)
5. Golla, Kishore: 2 articles (01/2013 - 01/2012)
6. Pasquini, Juana M: 2 articles (10/2012 - 01/2003)
7. Sahlstedt, Leila: 2 articles (03/2004 - 06/2003)
8. Ebeling, Freja: 2 articles (03/2004 - 06/2003)
9. Ruutu, Tapani: 2 articles (03/2004 - 06/2003)
10. Baek, Jin Hyen: 1 article (05/2015)

Related Diseases

1. Neoplasms (Cancer)
08/23/1980 - "It is suggested that this oncofetal receptor preferentially binds apotransferrin and may offer a novel approach to more specific therapy of certain breast cancers."
10/01/2005 - "(111)In-hnTf-VEGF accumulated in U87MG tumors (6.7% injected dose per gram at 72 h after injection) and its tumor uptake decreased 15-fold by coadministration of a 100-fold excess of VEGF but not by apotransferrin. "
01/01/1996 - "Recently, it has been shown that both complexes bind specifically to human serum apotransferrin and the resulting adducts have been studied through spectroscopic and chromatographic techniques with the ultimate goal of preparing adducts with good selectivity for cancer cells due to the fact that tumour cells express high amounts of transferrin receptors on their cell surface.In"
01/04/1995 - "We measured the amount of growth inhibition by suramin in low serum assays to demonstrate maximal inhibition over the apotransferrin to reverse the inhibition of suramin in these tumors. "
01/01/1996 - " order to investigate whether the cellular uptake of the complexes was mediated by apotransferrin or transferrin, we compared the antiproliferative efficacy of HInd[RuInd(2)Cl(4)] and HIm[RuIm(2)Cl(4)] with its apotransferrin- and transferrin-bound form in the human colon cancer cell line SW707 using the microculture tetrazolium test (MTT).Our results show that especially the transferrin-bound forms exhibit high antiproliferative activity, which exceeds that of the free complex, indicating that this protein can act as a carrier of the ruthenium complexes into the tumor cell."
2. Lung Injury
3. Colonic Neoplasms (Colon Cancer)
4. Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain)
5. Anemia

Related Drugs and Biologics

1. Lactoferrin
2. Doxorubicin (Adriamycin)
3. lactoferrin receptors
4. Hemoglobins (Hemoglobin)
5. Transferrin (beta 2 Transferrin)
6. Ruthenium
7. Iron
8. Hormones
9. Triiodothyronine (Liothyronine)
10. Deferoxamine (Desferal)

Related Therapies and Procedures

1. Transplants (Transplant)
2. Transplantation (Transplant Recipients)