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homocitric acid

Also Known As:

homocitrate

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Tricarboxylic Acids: 423
      - homocitric acid: 4

Experts

1.	Jia, Yunhua: 2 articles (10/2008 - 06/2006)
2.	Palmer, David R J: 2 articles (10/2008 - 06/2006)
3.	Breen, Paul: 1 article (01/2022)
4.	Caverly, Lindsay J: 1 article (01/2022)
5.	Opron, Kristopher: 1 article (01/2022)
6.	Zimbric, Madsen: 1 article (01/2022)
7.	Dance, Ian: 1 article (05/2011)
8.	Drevland, Randy M: 1 article (10/2008)
9.	Graham, David E: 1 article (10/2008)
10.	Nishiyama, Makoto: 1 article (06/2006)

Related Diseases

1.	Infections 01/01/2022 - "The data obtained in this study identified several metabolic profile differences in sputum associated with NTM infection in CF, including 2-methylcitrate/homocitrate and selected ceramides. "
2.	Dehydration (Water Stress) 06/15/2006 - "HACN catalyses the hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, but the HACN-catalysed dehydration of (R)-homocitrate to cis-homoaconitate has not been observed in vitro. " 05/28/2011 - "It is suggested that the difference between Mo-nitrogenase and V-nitrogenase occurs in the immediately surrounding protein, which facilitates (possibly via water associated with homocitrate bound to V) the exogenous protonation and dehydration of -COH intermediates." 10/24/2008 - "The MJ1003 and MJ1271 proteins from the methanogen Methanocaldococcus jannaschii formed the first homoaconitase shown to catalyze both the dehydration of (R)-homocitrate to form cis-homoaconitate, and its hydration is shown to produce homoisocitrate. " 06/15/2006 - "We do not observe HACN-catalysed 'homocitrate dehydratase' activity; however, we have observed that ACN can catalyse the dehydration of (R)-homocitrate to cis-homoaconitate, but HACN is required for subsequent conversion of cis-homoaconitate into homoisocitrate. "

Related Drugs and Biologics

1.	Ceramides
2.	Proteins (Proteins, Gene)
3.	homoisocitric acid
4.	Nitrogenase
5.	Hydro-Lyases (Dehydratases)
6.	homoaconitate hydratase
7.	3-hydroxy-5-estrane-17-carbonitrile (ACN)