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ACTH (4-9)
Also Known As:
ACTH 4-9; ACTH(4-9); L-Tryptophan, N-(N(2)-(N-(N-(N-L-methionyl-L-alpha-glutamyl)-L-histidyl)-L-phenylalanyl)-L-arginyl)-
Networked:
15
relevant articles (
4
outcomes,
9
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Hormones, Hormone Substitutes, and Hormone Antagonists
Hormones: 80400
Peptide Hormones: 1347
Pituitary Hormones: 601
Anterior Pituitary Hormones: 187
Pro-Opiomelanocortin: 1936
Melanocortins: 946
Adrenocorticotropic Hormone: 16568
ACTH (4-9): 15
Hypothalamic Hormones: 68
Pro-Opiomelanocortin: 1936
Melanocortins: 946
Adrenocorticotropic Hormone: 16568
ACTH (4-9): 15
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Nerve Tissue Proteins: 2
Neuropeptides: 6772
Hypothalamic Hormones: 68
Pro-Opiomelanocortin: 1936
Melanocortins: 946
Adrenocorticotropic Hormone: 16568
ACTH (4-9): 15
Peptides: 82426
Neuropeptides: 6772
Hypothalamic Hormones: 68
Pro-Opiomelanocortin: 1936
Melanocortins: 946
Adrenocorticotropic Hormone: 16568
ACTH (4-9): 15
Peptide Hormones: 1347
Pituitary Hormones: 601
Anterior Pituitary Hormones: 187
Pro-Opiomelanocortin: 1936
Melanocortins: 946
Adrenocorticotropic Hormone: 16568
ACTH (4-9): 15
Hypothalamic Hormones: 68
Pro-Opiomelanocortin: 1936
Melanocortins: 946
Adrenocorticotropic Hormone: 16568
ACTH (4-9): 15
Peptide Fragments: 373
ACTH (4-9): 15
Related Diseases
1.
Ototoxicity
10/01/1998 - "
Protective effects of a neurotrophic ACTH(4-9) analog on cisplatin ototoxicity in relation to the cisplatin dose: an electrocochleographic study in albino guinea pigs.
"
10/01/1998 - "
This study showed that the ACTH(4-9) analog partially prevents the ototoxicity of cisplatin.
"
01/01/1994 - "
Application of a neuroprotective ACTH(4-9) analog to affect cisplatin ototoxicity: an electrocochleographic study in guinea pigs.
"
10/01/1998 - "
Hamers et al. (1994) studied electrophysiologically the effect of an ACTH(4-9) analog, also known as ORG2766, on the ototoxicity of cisplatin (administered at 2 mg/kg/day for 8 days) in guinea pigs.
"
10/01/1998 - "
Recently, the effect of the ACTH(4-9) analog, ORG2766, on cisplatin ototoxicity was studied by Hamers et al. (1994).
"
2.
Testicular Neoplasms (Testicular Cancer)
06/01/1994 - "
The effects of an ACTH (4-9) analogue on development of cisplatin neuropathy in testicular cancer: a randomized trial.
"
06/01/1994 - "
These results show that Org 2766 cannot completely prevent cisplatin neuropathy in young men with testicular cancer, but nerve damage may be ameliorated by the use of this ACTH (4-9) analogue.
"
06/01/1994 - "
The efficacy of the ACTH (4-9) analogue Org 2766 in the prevention of subclinical cisplatin neuropathy was assessed in a double-blind placebo-controlled multi-centre study in patients with testicular cancer or adenocarcinoma of unknown primary.
"
3.
Ovarian Neoplasms (Ovarian Cancer)
01/11/1990 - "
Prevention of cisplatin neurotoxicity with an ACTH(4-9) analogue in patients with ovarian cancer.
"
01/11/1990 - "
In a randomized, double-blind, placebo-controlled study, we assessed the efficacy of an ACTH(4-9) analogue, Org 2766, in the prevention of cisplatin neuropathy in 55 women with ovarian cancer.
"
4.
Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/01/1984 - "
The present study compared the efficacy of ACTH 4-9 analog, methylphenidate, and placebo on attention deficit disorder with 30 (HK) children with attention deficit disorder and psychometric measurements.
"
01/01/1984 - "
Efficacy of ACTH 4-9 analog, methylphenidate, and placebo on attention deficit disorder with hyperkinesis.
"
5.
Adenocarcinoma
06/01/1994 - "
The efficacy of the ACTH (4-9) analogue Org 2766 in the prevention of subclinical cisplatin neuropathy was assessed in a double-blind placebo-controlled multi-centre study in patients with testicular cancer or adenocarcinoma of unknown primary.
"
Related Drugs and Biologics
1.
Cisplatin (Platino)
2.
Org 2766
3.
Methylphenidate (Ritalin)
4.
lysylphenylalanine
5.
hydroxide ion
6.
Cytostatic Agents
7.
Vincristine (Oncovin)
8.
Peptides (Polypeptides)
9.
Nerve Growth Factors (Neurotrophins)
10.
Adrenocorticotropic Hormone (ACTH)