|1.||Kuo, Chih-Feng: 7 articles (01/2015 - 05/2004)|
|2.||Tsao, Nina: 5 articles (01/2015 - 01/2006)|
|3.||Lin, Yee-Shin: 5 articles (08/2012 - 05/2004)|
|4.||Rincon, Jaimar: 4 articles (05/2009 - 06/2003)|
|5.||Chuang, Woei-Jer: 4 articles (03/2008 - 05/2004)|
|6.||Wu, Jiunn-Jong: 3 articles (08/2012 - 05/2004)|
|7.||Viera, Ninoska: 3 articles (05/2009 - 01/2006)|
|8.||Mosquera, Jesus: 3 articles (05/2009 - 01/2006)|
|9.||Wang, Yu-Chieh: 2 articles (01/2015 - 01/2013)|
|10.||Yang, Hsiu-Chen: 2 articles (01/2015 - 01/2013)|
12/01/1926 - "STUDIES IN SCARLET FEVER: I. The Amount of Scarlatinal Toxin in the Blood of Patients with Scarlet Fever."
07/01/1997 - "Twenty-five throat isolates of Streptococcus pyogenes (GAS, group A streptococcus) available from 24 children, including 10 children with scarlet fever and 14 asymptomatic carriers, and one asymptomatic staff member were studied for the presence of genes encoding streptococcal pyrogenic exotoxin types A (speA), B (speB), and C (speC) and for protease activity. "
06/01/1989 - "Group A streptococcal pyrogenic exotoxin (scarlet fever toxin) type A and blastogen A are the same protein."
08/01/1987 - "Reference strains of Streptococcus pyogenes and strains from recent epidemics and sporadic cases of scarlet fever were examined for their ability to produce erythrogenic toxin type A (ET A) by ELISA and double immunodiffusion (Ouchterlony) using an anti-ET A antibody purified by affinity chromatography. "
09/01/1983 - "The high prevalence of erythrogenic, toxin-producing strains is difficult to reconcile with the epidemiologic behavior of scarlet fever; the variations may be due to quantitative differences in toxin production or to a shift from the early scarlet fever-associated strains that produce A toxin to the currently prevalent strains that produce B and C toxins. "
09/15/2001 - "This study compared the pathology and infection pattern of streptococcal pyrogenic exotoxin B-positive (SpeB(+)) and SpeB-negative (SpeB(-)) isogenic variants of an M1 isolate of Streptococcus pyogenes in a mouse skin air sac model. "
11/30/2001 - "The streptococcal pyrogenic exotoxin B (SpeB) is an important factor in mediating Streptococcus pyogenes infections. "
04/01/1998 - "High-frequency intracellular infection and erythrogenic toxin A expression undergo phase variation in M1 group A streptococci."
11/01/1988 - "The impact of anti-erythrogenic toxin and toxoid immunity was investigated under the conditions of experimental infection with the ET A-producing Streptococcus pyogenes strain SF 130 (type 1). "
11/01/1988 - "III. Influence of immunization with erythrogenic toxin type A (ET A) and its toxoid on subsequent infection with an ET A producing strain."
06/01/1998 - "This study evaluated a PCR assay for detection of the streptococcal pyrogenic exotoxin B (speB) gene from tissue biopsy specimens of patients with necrotizing fasciitis. "
06/01/1998 - "Diagnosis of group A streptococcal necrotizing fasciitis by using PCR to amplify the streptococcal pyrogenic exotoxin B gene."
02/29/2000 - "We have determined the crystal structure of streptococcal pyrogenic exotoxin B (SpeB), a cysteine protease that is a major virulence factor of the human pathogen Streptococcus pyogenes and participates in invasive disease episodes, including necrotizing fasciitis. "
|4.||Septic Shock (Toxic Shock Syndrome)
04/01/2005 - "Previously, we have performed T typing of Streptococcus pyogenes strains isolated from patients with streptococcal toxic shock syndrome (STSS) in Japan, and streptococcal pyrogenic exotoxin (SPE) typing for epidemiological examination. "
08/01/1994 - "Possible synergistic effects of toxic shock syndrome toxin 1 and streptococcal pyrogenic exotoxin C."
03/01/1993 - "Staphylococcus aureus toxic shock syndrome toxin 1 and Streptococcus pyogenes erythrogenic toxin A modulate inflammatory mediator release from human neutrophils."
12/15/1992 - "Thus, it is difficult to define a specific role for erythrogenic toxin B in toxic shock-like syndrome as there was no clear correlation between this disease and the presence of toxin genes. "
12/15/1992 - "In contrast to reports indicating that 85% of the toxic shock-like syndrome-associated isolates contained the erythrogenic toxin A gene, only 58.5% of our strains harboured this gene. "
|5.||Streptococcal Infections (Streptococcal Infection)
01/01/2015 - "Application of the C3-binding motif of streptococcal pyrogenic exotoxin B to protect mice from invasive group a streptococcal infection."
02/01/2007 - "Streptococcal pyrogenic exotoxin B (SPE B) is a virulent factor in group A streptococcal infection. "
11/01/2006 - "Severe, invasive group A streptococcal infections have reemerged worldwide, and extracellular toxins, including streptococcal pyrogenic exotoxin B (SpeB), have been implicated in pathogenesis. "
05/01/2004 - "Histopathologic changes in kidney and liver correlate with streptococcal pyrogenic exotoxin B production in the mouse model of group A streptococcal infection."
08/01/1998 - "Role of streptococcal pyrogenic exotoxin B in the mouse model of group A streptococcal infection."
|2.||Cysteine Proteases (Cysteine Protease)
|3.||Streptococcus pyogenes SpeA protein
|5.||Virulence Factors (Pathogenicity Factors)
|10.||Heat-Shock Proteins (Heat-Shock Protein)