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domiodol
RN given refers to cpd with unspecified stereochemistry
Also Known As:
2-iodomethyl-4-oxymethyl-1,3-dioxolane; 4-hydroxymethyl-2-iodomethyl-1,3-dioxolane; 4-hydroxymethyl-2-iodomethyl-1,3-dioxolane, cis-isomer; 4-hydroxymethyl-2-iodomethyl-1,3-dioxolane, trans-isomer; M.G. 13608; cis,trans-4-hydroxymethyl-2-iodomethyl-1,3-dioxolane
Networked:
4
relevant articles (
1
outcomes,
1
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Dioxoles
Dioxolanes: 3
domiodol: 4
Related Diseases
1.
Infections
01/01/1988 - "
Thus, domiodol proved effective in reducing the symptoms of infection of the lower respiratory tract and in improving the consistency of mucus in children.
"
2.
Chronic Obstructive Pulmonary Disease (COPD)
11/01/1982 - "
The results of a double-blind trial on the clinical and functional effects induced by domiodol and S-carboxymethylcysteine (SCMC) on 40 patients with chronic obstructive lung disease are discussed.
"
11/01/1982 - "
Double-blind clinical trial of domiodol vs S-carboxymethylcysteine in chronic obstructive lung disease.
"
3.
Chronic Bronchitis
01/01/1988 - "
Thirty children (25 males, five females), mean age 9.33 +/- 2.57 years, with acute infectious pulmonary diseases or acute flare-ups of chronic bronchitis, were randomly treated with either domiodol or placebo.
"
05/26/1981 - "
A double-blind study has been carried out in adult patients suffering from acute and chronic bronchitis, and acute exacerbation of chronic hypersecretory bronchitis, excluding the bronchorreic forms, in order to evaluate the mucolytic activity of orally given domiodol and sobrerol.
"
4.
Bronchitis
01/01/1983 - "
In addition, oral domiodol (50 and 100 mg/kg) significantly reduced the viscosity of sputum collected quantitatively from rabbits with subacute bronchitis induced by long-term exposure to SO2 gas; the percentage decrease in viscosity was statistically correlated with the content of dry matter, protein and polysaccharides in the sputum.
"
05/26/1981 - "
A double-blind study has been carried out in adult patients suffering from acute and chronic bronchitis, and acute exacerbation of chronic hypersecretory bronchitis, excluding the bronchorreic forms, in order to evaluate the mucolytic activity of orally given domiodol and sobrerol.
"
5.
Lung Diseases (Lung Disease)
01/01/1988 - "
Thirty children (25 males, five females), mean age 9.33 +/- 2.57 years, with acute infectious pulmonary diseases or acute flare-ups of chronic bronchitis, were randomly treated with either domiodol or placebo.
"
Related Drugs and Biologics
1.
Carbocysteine (S-Carboxymethylcysteine)
2.
Proteins (Proteins, Gene)
3.
Polysaccharides (Glycans)
4.
Expectorants (Mucolytics)
5.
sobrerol