milbemycin (moxidectin)

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164 relevant articles (55 outcomes, 20 trials/studies) found for this Bio-Agent

Description: family of macrolide antibiotics with insecticidal & acaricidal activity; RN given refers to cpd with unknown MF; structure in first source; moxidectin (CL 301,423) is milbemycin B

Also Known As:

moxidectin; 5-hydroxymilbemycin beta7; CL 301,423; CL 301423; Cydectin; milbemycin A3; milbemycin A4; milbemycin B; milbemycin D; milbemycin alpha1; milbemycin alpha10; milbemycin alpha11; milbemycin alpha13; milbemycin alpha14; milbemycin alpha15; milbemycin alpha2; milbemycin alpha3; milbemycin alpha4; milbemycin alpha5; milbemycin alpha6; milbemycin alpha7; milbemycin alpha8; milbemycin alpha9; milbemycin beta1; milbemycin beta12; milbemycin beta2; milbemycin beta3; milbemycins

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 42

Lactones: 151

Macrolides: 803

milbemycin: 164

Polycyclic Compounds: 59

Macrocyclic Compounds: 2

Experts

1.	Arther, R G: 5 articles (08/2007 - 07/2003)
2.	Heaney, Kathleen: 3 articles (10/2005 - 01/2003)
3.	Genchi, Marco: 2 articles (06/2008 - 12/2002)
4.	Venco, Luigi: 2 articles (06/2008 - 12/2002)
5.	Genchi, Claudio: 2 articles (06/2008 - 12/2002)
6.	Heine, J: 2 articles (08/2007 - 10/2005)
7.	Ciszewski, D K: 2 articles (08/2007 - 10/2005)
8.	Davis, W L: 2 articles (08/2007 - 10/2005)
9.	Alvinerie, Michel: 2 articles (11/2006 - 03/2003)
10.	Lok, James B: 2 articles (10/2005 - 03/2005)

Related Diseases

1.	Infection 04/15/2006 - "Study results demonstrate QG, administered to horses with naturally acquired endoparasite infections at a dosage of 0.4 mg moxidectin/kg b.w., was highly effective against a broad range of equine parasitic infections." 11/01/2004 - "A single SC injection of a sustained-release formulation of moxidectin was effective in providing protection against heartworm infection after 12 months in dogs. " 11/01/2004 - "OBJECTIVE: To evaluate the efficacy of a single injection of a sustained-release formulation of moxidectin in preventing heartworm (Dirofilaria immitis) infection for 12 months in dogs. " 03/01/2000 - "In addition to demonstrating the boticidal efficacy of moxidectin, this trial illustrated that gastroscopy/duodenoscopy is a feasible method for confirming infections with different species of bot larvae in the horse." 06/25/2003 - "Necropsy results from two of three monitor calves slaughtered on Day 6 after infection indicated that Day 6 was an appropriate time to evaluate efficacy of moxidectin against fourth larval stages (L(4)). " Order ALL the reference details at left...
2.	Nematode Infections 03/01/1992 - "The efficacy of moxidectin, a new endectocide against natural nematode infections, was evaluated. " 11/25/2005 - "The efficacy of 0.5% moxidectin pour-on in cows with naturally acquired nematode infections was evaluated. " 11/25/2005 - "Efficacy of moxidectin 0.5% pour-on against naturally acquired nematode infections in cattle in the Mexican tropics." 01/15/1998 - "Efficacy of moxidectin 2% equine gel against natural nematode infections in ponies." 10/15/1996 - "The efficacy of 0.5% moxidectin pour-on at two dosages was evaluated in 30 cattle with naturally acquired gastrointestinal nematode infections. " Order ALL the reference details at left...
3.	Mite Infestations (Mange) 01/01/2005 - "A single dose of topical moxidectin as an effective treatment for murine acariasis due to Myocoptes musculinus." 11/01/1998 - "We report the efficacy of moxidectin (SC, 200 mcg/kg, b.w.) in a repeated treatment program of 7-10 d, which is currently used for mange control in these ruminants." 01/01/2005 - "To the authors' knowledge, this is the first report of topical moxidectin as a treatment for murine acariasis." 06/30/1999 - "The use of moxidectin for the prevention and treatment of psoroptic mange (scab) in sheep." 11/02/1996 - "Treatment and control of psoroptic mange (sheep scab) with moxidectin." Order ALL the reference details at left...
4.	Body Weight (Weight, Body) 10/01/1998 - "CONCLUSIONS: The pour-on formulation of moxidectin, at 500 microg/kg body weight, is highly effective against mature and immature lungworms and abomasal nematodes in wapiti hybrid deer and equally effective in red deer." 02/01/1995 - "Treatment with moxidectin in single doses of 300, 400, or 500 micrograms/kg of body weight was 100% effective in eliminating microfilariae from 20 skin biopsies taken 14 days posttreatment, whereas 5 microfilaria-positive ponies in 2 control groups remained positive following placebo treatment. " 07/20/2007 - "The bioavailability of this long-acting formulation of moxidectin is similar to that registered after subcutaneous administration of moxidectin in cattle at 0.2 mg kg(-1) body weight. " 06/01/2006 - "canis, were treated subcutaneously with 1 mg moxidectin per kg body weight on days 40 and 55 of pregnancy (5-13 days before parturition). " 11/25/2005 - "Animals in the treated group received 0.5% moxidectin pour-on at a dose of 0.5 mg/kg body weight on a single occasion. " Order ALL the reference details at left...
5.	Weight Gain 04/30/2006 - "The effectiveness, safety and production-enhancing benefit (improved weight gains) of moxidectin long-acting injection given subcutaneously in the ear at the rates of 0.75, 1.0 and 1.5mg/kg bw were evaluated in three studies under common protocol. " 04/01/2009 - "However, following treatment with long-acting moxidectin in winter, ewes had rapid compensatory weight gain and lower egg output than ewes treated in summer. " 01/01/2006 - "Moxidectin long-acting injection provided efficacious (immediate as well as long-term) egg count suppressions as well as enhanced animal productivity (weight gains). " 12/15/2004 - "Rate of weight gain by cattle treated with moxidectin LA injectable was 0.59 kg/day, or 23% (0.11 kg/day) more than placebo-treated controls (P<0.05). " 12/15/2004 - "Effects of subcutaneous injections of a long acting moxidectin formulation in grazing beef cattle on parasite fecal egg reduction and animal weight gain." Order ALL the reference details at left...

Related Drugs and Biologics

1.	Ivermectin (Mectizan)
2.	doramectin
3.	imidacloprid
4.	milbemycin (moxidectin)
5.	Tablets
6.	4''-epiacetylamino-4''-deoxyavermectin B1 (eprinomectin)
7.	milbemycin oxime (Interceptor)
8.	fluphenacur (lufenuron)
9.	Fenbendazole
10.	Levamisole (Decaris)

Related Therapies and Procedures

1.	Injections
2.	Aftercare (After-Treatment)
3.	Subcutaneous Injections
4.	Microspheres (Microsphere)
5.	Drug Therapy (Chemotherapy)

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