HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

Cain quinolinium

structure given in first source

Also Known As:

Cain's quinolinium; NSC 113089

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - Quinolinium Compounds: 1
        Cain quinolinium: 2

Related Diseases

1.	Neoplasms (Cancer) 01/01/1979 - "The binding characteristics of the cancer chemotherapeutic Cain's quinolinium 6-amino-1-ethyl-4-[p-[[p-[(1-ethylpyridinium-4-yl) amino] phenyl] carbamoyl]-anilino]-quinolinium dibromide (NSC 113089) to lipid extracts from rat kidney, liver, heart and skeletal muscle has been studied. "
2.	Leukemia L1210 10/01/1981 - "However, treatment of murine L1210 leukemia bearing mice with the combination of Cain's Quinolinium and mechlorethamine at a mole ratio of 1:1 resulted in 100% long term survivors compared to 50% with Cain's Quinolinium alone or 0% with mechlorethamine alone." 10/01/1981 - "Cain's Quinolinium; quinolinium, 6-amino-1-methyl-4[[[[[[(1-methyl-pyridinium-4-yl)amino]phenyl]amino]carbonyl]phenyl]amino] (NSC 176319), is a chemotherapeutic agent, which is equally cytotoxic in vitro to both murine L1210 leukemia cells and bone marrow progenitor cells. " 10/01/1981 - "Cain's quinolinium (NSC 176319): protection of murine L1210 leukemia cells and bone marrow progenitor cells against mechlorethamine cytotoxicity and its application to combination chemotherapy."

Related Drugs and Biologics

1.	Cain quinolinium
2.	quinolinium dibromide (QdB)
3.	Mechlorethamine (Nitrogen Mustard)
4.	Lipids
5.	ethylpyridinium

Related Therapies and Procedures

1.	Combination Drug Therapy (Combination Chemotherapy)