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naphthalene-1,5-dimaleimide

Also Known As:

NDMI; 1H-Pyrrole-2,5-dione, 1,1'-(1,5-naphthalenediyl)bis-

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Dicarboxylic Acids: 108
      - Maleates: 3
        Maleimides: 16
        naphthalene-1,5-dimaleimide: 3
- Imides: 79
  - Maleimides: 16
    - naphthalene-1,5-dimaleimide: 3
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - Maleimides: 16
        naphthalene-1,5-dimaleimide: 3

Related Diseases

1.	Glioma (Gliomas) 10/28/2022 - "In adult whole blood samples, the linear composite scores from NDMI 450 and NDMI 850 were highly correlated and had equivalent predictive accuracy for detecting DEX exposure among adult glioma patients and non-glioma adult controls. " 01/01/2022 - "The NDMI is associated with low CD4 T cells and the accumulation of monocytic myeloid-derived suppressor cells and also serves as prognostic factor in glioma survival. " 01/01/2022 - "In a non-glioma population, the NDMI increases with a history of prednisone use. "
2.	Inflammation (Inflammations) 10/28/2022 - "The neutrophil dexamethasone methylation index (NDMI 850) is a blood-based DNA methylation biomarker built on the Illumina MethylationEPIC (850K) array that measures epigenetic responses to dexamethasone (DEX), a synthetic glucocorticoid often administered for inflammation. "
3.	Hepatocellular Carcinoma (Hepatoma) 04/01/1984 - "Of the rats given the high dose of NDMI 50% died with hepatocellular carcinomas, as did 8% of the rats receiving the lower dose and 0.5% of untreated rats (p less than 0.001). "

Related Drugs and Biologics

1.	Biomarkers (Surrogate Marker)
2.	Prednisone (Sone)
3.	Glucocorticoids
4.	Dexamethasone (Maxidex)