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benzo(j)fluoranthene

dihydrodiol metabolites identified as mutagens; structure given in first source

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Fluorenes: 7
        benzo(j)fluoranthene: 4
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Fluorenes: 7
    - benzo(j)fluoranthene: 4

Experts

1.	Delerue-Matos, Cristina: 1 article (11/2020)
2.	Duarte, Sofia: 1 article (11/2020)
3.	Morais, Simone: 1 article (11/2020)
4.	Oliveira, Marta: 1 article (11/2020)
5.	Pena, Angelina: 1 article (11/2020)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1982 - "The tumor initiating activities on mouse skin of benzo[b]fluoranthene, (B[b]F), benzo[j]fluoranthene (B[j]F), benzo[k]fluoranthene (B[k]F] and three of their dihydrodiols, 9,10-dihydro-9,10-dihydroxybenzo[b]fluoranthene (B[b]F-9,10-diol), 9,10-dihydro-9,10-dihydroxybenzo[j]fluoranthene (B[j]F-9,10-diol), and 8,9-dihydro-8,9-dihydroxybenzo[k]fluoranthene (B[k]F-8,9-diol) were evaluated. " 06/15/1993 - "Exceptional tumor-initiating activity of 4-fluorobenzo[j]-fluoranthene on mouse skin: comparison with benzo[j]-fluoranthene, 10-fluoro-benzo[j]fluoranthene, benzo[a]pyrene, dibenzo[a,l]pyrene and 7,12-dimethylbenz[a]anthracene."
2.	Carcinogenesis 12/01/1992 - "Treatment of the cells with ethanol did not significantly increase the uptake of a polycyclic aromatic hydrocarbon, benzo[j]fluoranthene, however, high tar CSC alone or in combination with ethanol significantly increased the uptake of radiolabeled benzo[j]fluoranthene, suggesting that increased uptake of the carcinogens may be one of the synergistic mechanisms of alcohol in oral carcinogenesis."
3.	Body Weight (Weight, Body) 11/01/2020 - "Breast-fed infant presented a median PAHs daily intake of 1.41 μg/kg body weight (total benzo(a)pyrene equivalents of 0.0679 μg/kg) and were exposed to 0.024 μg/kg body weight of ∑PAH4 [benz(a)anthracene, benzo(b)fluoranthene, benzo(j)fluoranthene, and chrysene]. "

Related Drugs and Biologics

1.	Benzo(a)pyrene
2.	fluoranthene
3.	benzo(b)fluoranthene
4.	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)
5.	Carcinogens
6.	Ethanol (Ethyl Alcohol)
7.	dibenzo(a,l)pyrene
8.	anthracene
9.	chrysene
10.	benz(a)anthracene (benzanthracene)