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isonicotinamide

Also Known As:

4-pyridinecarboxamide

Networked: 14 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Nicotinic Acids: 13
      - Niacinamide: 2223
        isonicotinamide: 14
- Heterocyclic Acids
  - Nicotinic Acids: 13
    - Niacinamide: 2223
      - isonicotinamide: 14

Experts

1.	Anwaier, Gulinigaer: 1 article (12/2022)
2.	Di, Chang: 1 article (12/2022)
3.	Hu, Rui: 1 article (12/2022)
4.	Huang, Yanbin: 1 article (12/2022)
5.	Qi, Rong: 1 article (12/2022)
6.	Wang, Anyi: 1 article (12/2022)
7.	Wang, Qinyu: 1 article (12/2022)
8.	Wang, Yunxia: 1 article (12/2022)
9.	Yang, Xiaotong: 1 article (12/2022)
10.	Zhang, Xing: 1 article (12/2022)

Related Diseases

1.	Neoplasms (Cancer) 10/01/2007 - "Here we show that one of these new compounds, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), is potently effective against various resistant and nonresistant cancer cell lines despite the status of multidrug resistance, multidrug-resistance associated protein, or other resistance factors in vitro. " 10/01/2007 - "A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule." 06/01/2004 - "nicotinamide, isonicotinamide or nicotinic acid, as extra (axial) ligands, were tested in vivo on transplanted mice tumors, namely Lewis lung carcinoma (3LL), melanoma B16, and mammary adenocarcinoma Ca755. "
2.	Abdominal Aortic Aneurysm 12/01/2022 - "HPMC improves protective effects of naringenin and isonicotinamide co-crystals against abdominal aortic aneurysm."
3.	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 06/01/2000 - "In human chronic myelogenous leukemia cells, K562, which are relatively resistant to various inducers of apoptosis, the apoptosis was induced by picolinic acid and dipicolinic acid in about 50% of the cells 5-10 mM via the caspase pathway, but was not at 1 mM. However, isonicotinamide did not induce apoptosis effectively in K562 cells. " 10/01/1999 - "After treatments with picolinic acid, dipicolinic acid, and isonicotinamide, apoptosis started within 4 hr and it was induced in about 50% of the cells within 8 hr. These compounds also induced apoptosis in human chronic myelogenous leukemia cells, K562 and human cervical carcinoma cells, HeLa. "
4.	Lewis Lung Carcinoma 06/01/2004 - "nicotinamide, isonicotinamide or nicotinic acid, as extra (axial) ligands, were tested in vivo on transplanted mice tumors, namely Lewis lung carcinoma (3LL), melanoma B16, and mammary adenocarcinoma Ca755. "
5.	Acute Myelomonocytic Leukemia 10/01/1999 - "It was found that picolinic acid, dipicolinic acid, and isonicotinamide strongly induce apoptosis in human acute myelomonocytic leukemia cells, HL-60. "

Related Drugs and Biologics

1.	Multidrug Resistance-Associated Proteins
2.	naringenin
3.	Niacinamide (Nicotinamide)
4.	picolinic acid (chromium picolinate)
5.	dipicolinic acid
6.	Caspases
7.	Sulfonamides
8.	Ruthenium
9.	Niacin (Nicotinic Acid)
10.	Ligands

Related Therapies and Procedures

1.	Aftercare (After-Treatment)