|1.||Cho, Jae Youl: 2 articles (11/2013 - 04/2013)|
|2.||Hong, Sungyoul: 2 articles (11/2013 - 04/2013)|
|3.||Kim, Ji Hye: 2 articles (11/2013 - 04/2013)|
|4.||Yoo, Byong Chul: 2 articles (11/2013 - 04/2013)|
|5.||Sandri-Goldin, Rozanne M: 2 articles (09/2009 - 06/2009)|
|6.||Souki, Stuart K: 2 articles (09/2009 - 06/2009)|
|7.||Kim, Kyung-Hee: 1 article (11/2013)|
|8.||Kim, Jong Heon: 1 article (11/2013)|
|9.||Lee, Jae Yong: 1 article (11/2013)|
|10.||Kim, Han Gyung: 1 article (11/2013)|
06/01/2009 - "Most striking was the finding that under conditions of hypomethylation resulting from infection with arginine substitution mutants or treatment of wild-type HSV-1-infected cells with the methylation inhibitor adenosine dialdehyde, ICP27 export to the cytoplasm occurred earlier and was more rapid than wild-type ICP27 export. "
09/01/2009 - "During infections with viral mutants containing lysine substitutions or the methylation inhibitor adenosine dialdehyde, the interaction of ICP27 with SRPK1 and Aly/REF was decreased, as determined by coimmunoprecipitation and colocalization studies, indicating that ICP27 RGG box methylation regulates interaction with these proteins."
05/01/1987 - "Treatment of L cells with 5 microM adenosine dialdehyde for 60 min prior to virus infection causes a transient, but virtually complete loss of S-adenosylhomocysteine hydrolase activity and subsequent 3-fold increase in the intracellular S-adenosylhomocysteine/S-adenosylmethionine ratio. "
11/15/1990 - "In a previous study [Cools M and De Clercq E, Biochem Pharmacol 38: 1061-1067, 1989], we found a close correlation between the antiviral activity of six adenosine analogues [S)-9-(2,3-dihydroxypropyl)adenine [(S)-DHPA], (RS)-3-adenin-9-yl-2-hydroxypropanoic acid [(RS)-AHPA] (isobutyl ester), 3-deazaneplanocin A, carbocyclic 3-deazaadenosine (C-c3 Ado), adenosine dialdehyde and neplanocin A) against vaccinia virus and vesicular stomatitis virus and the inhibitory effect of these compounds on purified AdoHcy hydrolase isolated from murine L929 cells. "
|3.||Prostatic Neoplasms (Prostate Cancer)
07/01/2012 - "Results indicate that the methyltransferase inhibitor adenosine dialdehyde is a promising, novel therapeutic compound for prostate cancer."
07/01/2012 - "The cytotoxic effect of adenosine dialdehyde on prostate cancer was also evaluated in vitro and in vivo. "
07/01/2012 - "Adenosine dialdehyde also suppressed prostate cancer growth in vivo in a mouse xenograft model. "
07/01/2012 - "As a result, adenosine dialdehyde had a cytotoxic effect on androgen dependent, androgen sensitive and castration resistant prostate cancer cells in vitro. "
07/01/2012 - "Methyltransferase inhibitor adenosine dialdehyde suppresses androgen receptor expression and prostate cancer growth."
|4.||Hepatocellular Carcinoma (Hepatoma)
11/01/2013 - "Adenosine dialdehyde suppresses MMP-9-mediated invasion of cancer cells by blocking the Ras/Raf-1/ERK/AP-1 signaling pathway."
01/01/1991 - "For both tumor cells, DTH against unmodified cells was markedly potentiated by prevaccination with cells treated with hydrostatic pressure combined with adenosine dialdehyde. "
11/01/1988 - "The effect of adenosine dialdehyde (AD) on in situ tumor growth and host survival was evaluated in the C1300 murine neuroblastoma tumor model prepared by implantation of murine neuroblastoma cells into A/J mice. "
08/01/1998 - "Hydrostatic pressure (P) combined with membrane protein crosslinking (CL) by adenosine dialdehyde (AdA) can render tumor cells immunogenic. "
01/01/1991 - "In addition, increased [3H]thymidine uptake was observed in effector T cells induced by prevaccination with tumor cells modified by adenosine dialdehyde or pressure or both. "
|2.||Proteins (Proteins, Gene)
|9.||3-adenin-9-yl-2-hydroxypropanoic acid isobutyl ester
|1.||Heterologous Transplantation (Xenotransplantation)