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nocardicin (nocardicin A)
RN given refers to cpd with unknown MF
Also Known As:
nocardicin A
; nocarcidins; nocardicin A, sodium salt; nocardicin B; Nocardicin
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Lactams: 2198
nocardicin: 4
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Lactams: 2198
nocardicin: 4
Related Diseases
1.
Gram-Negative Bacterial Infections
05/01/1984 - "
These properties resulted in a broad spectrum of activity of the combination Nva -Ala(P) plus nocardicin A when used to treat experimental gram-negative bacterial infections.
"
2.
Pseudomonas Infections
04/01/1983 - "
Therapeutic significance of nocardicin A stimulation of phagocyte function in experimental Pseudomonas aeruginosa infection.
"
04/01/1983 - "
Nocardicin A, a monocyclic beta-lactam antibiotic with modest anti-pseudomonal activity in vitro, controlled an otherwise fatal Pseudomonas infection in mice when given in doses which produced blood levels well below the minimum bactericidal concentration.
"
3.
Infections
11/01/1977 - "
In addition, nocardicin A proved to be active against infections due to Serratia marcescens and other organisms resistant to beta-lactam antibiotics.
"
11/01/1977 - "
Nocardicin A was more potent in therapeutic effect than carbenicillin against infections due to Pseudomonas aeruginosa, Proteus mirabilis, Pr.
"
4.
Autolysis
03/01/1990 - "
Two temperature-sensitive autolysis-defective mutants of Escherichia coli were isolated and shown to be resistant to lysis induced by seminalplasmin, an antimicrobial protein from bovine seminal plasma, as well as to lysis induced by ampicillin, D-cycloserine and nocardicin, at 37 or 42 degrees C but not at 30 degrees C.
"
Related Drugs and Biologics
1.
Therapeutic Uses
2.
Proteins (Proteins, Gene)
3.
Monobactams (Monobactam Antibiotics)
4.
Cycloserine (Seromycin)
5.
Carbenicillin (Pyopen)
6.
Anti-Bacterial Agents (Antibiotics)
7.
Ampicillin (Omnipen)
8.
beta Lactam Antibiotics