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zetidoline
structure given in first source
Also Known As:
1-(3-chlorophenyl)-3-(2-(3,3-dimethyl-1-azetidinyl)ethyl)imidazolidin-2-one; DL 308-IT; DL-308; 2-Imidazolidinone, 1-(3-chlorophenyl)-3-(2-(3,3-dimethyl-1-azetidinyl)ethyl)-
Networked:
5
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Imidazoles: 150
zetidoline: 5
Related Diseases
1.
Schizophrenia (Dementia Praecox)
06/01/1984 - "
[Zetidoline in the treatment of schizophrenia--initial experiences].
"
12/01/1989 - "
Some parameters of the immune system at schizophrenia therapy with chlorpromazine and zetidoline.
"
09/01/1984 - "
Zetidoline (ZTD), a compound chemically unrelated to any available antipsychotic, with selective dopamine receptor-blocking properties, was compared with haloperidol (HLP) in a double-blind study on 56 in-patients who had either first episodes or acute relapses of schizophrenia.
"
2.
Miosis
01/01/1980 - "
DL-308, similarly to thioridazine, had effects consistent with an alpha-adrenolytic action; both drugs caused miosis, hypotension and a decrease in salivation.
"
3.
Hypotension (Low Blood Pressure)
01/01/1980 - "
DL-308, similarly to thioridazine, had effects consistent with an alpha-adrenolytic action; both drugs caused miosis, hypotension and a decrease in salivation.
"
4.
Herpes Zoster
01/01/1985 - "
Zetidoline applied by bath perfusion, was similarly an antagonist of the inhibitory effect of bath applications of dopamine on neurones in the zona compacta of slices of substantia nigra; the pA2 for zetidoline in this preparation was 7.0.
"
01/01/1985 - "
Zetidoline, applied microiontophoretically onto neurones in the substantia nigra, zona compacta of anaesthetized rats, reversibly blocked the depressant effect of iontophoretically-applied dopamine.
"
Related Drugs and Biologics
1.
Antipsychotic Agents (Antipsychotics)
2.
Thioridazine (Mellaril)
3.
Dopamine Receptors (Dopamine Receptor)
4.
Haloperidol (Haldol)
5.
Dopamine (Intropin)
6.
Chlorpromazine (Thorazine)
Related Therapies and Procedures
1.
Therapeutics