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tabernanthine

RN given refers to parent cpd

Also Known As:

tabernanthine tartrate; tabernanthine, p-chlorophenoxyacetate; 13-methoxyibogamine

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Hypoxia (Hypoxemia) 08/01/1980 - "Tabernanthine antagonized the effect of hypobaric hypoxia especially in dopaminergic areas. " 07/01/1984 - "Tabernanthine antagonized the decrease in hypothalamic 5-HT levels induced by a 7000 m hypoxia and also suppressed the decrease in PCPA-induced depletion observed at 5200 and 7000 m in the hypothalamus, the striatum and the rest of the brain. " 07/01/1984 - "Evidence for an antagonistic action of tabernanthine on hypoxia-induced changes in brain serotonin levels."
2.	Tremor (Tremors) 08/21/1987 - "Benzodiazepine receptors are involved in tabernanthine-induced tremor: in vitro and in vivo evidence." 08/21/1987 - "Moreover, tabernanthine-induced tremor was inhibited reversibly by flunitrazepam or by Ro-15 1788 (an antagonist of benzodiazepine-receptors). " 08/21/1987 - "In vivo, both tabernanthine and carbolines cause a fine general tremor, suggesting that a possible interaction with benzodiazepine receptors could be involved in the activity of tabernanthine. "
3.	Hypotension (Low Blood Pressure) 11/01/1981 - "1. Tabernanthine produced, in anaesthetized Rat and Dog, bradycardia and hypotension which remained after atropine or vagotomy. "
4.	Bradycardia 11/01/1981 - "3. Bradycardia occurred also after per os tabernanthine administration in unanaesthetized Dog. " 11/01/1981 - "1. Tabernanthine produced, in anaesthetized Rat and Dog, bradycardia and hypotension which remained after atropine or vagotomy. "

Related Drugs and Biologics

1.	Serotonin (5 Hydroxytryptamine)
2.	GABA-A Receptors (GABA(A) Receptor)
3.	Flunitrazepam (Rohypnol)
4.	Carbolines (Beta-Carbolines)
5.	Atropine

Related Therapies and Procedures

1.	Vagotomy