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tabernanthine
RN given refers to parent cpd
Also Known As:
tabernanthine tartrate; tabernanthine, p-chlorophenoxyacetate; 13-methoxyibogamine
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Alkaloids: 5398
Indole Alkaloids: 200
Secologanin Tryptamine Alkaloids: 81
Ibogaine: 157
tabernanthine: 4
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Indoles: 200
Indole Alkaloids: 200
Secologanin Tryptamine Alkaloids: 81
Ibogaine: 157
tabernanthine: 4
Ibogaine: 157
tabernanthine: 4
Indolizines: 3
Indolizidines: 2
Indole Alkaloids: 200
Secologanin Tryptamine Alkaloids: 81
Ibogaine: 157
tabernanthine: 4
Related Diseases
1.
Hypoxia (Hypoxemia)
08/01/1980 - "
Tabernanthine antagonized the effect of hypobaric hypoxia especially in dopaminergic areas.
"
07/01/1984 - "
Tabernanthine antagonized the decrease in hypothalamic 5-HT levels induced by a 7000 m hypoxia and also suppressed the decrease in PCPA-induced depletion observed at 5200 and 7000 m in the hypothalamus, the striatum and the rest of the brain.
"
07/01/1984 - "
Evidence for an antagonistic action of tabernanthine on hypoxia-induced changes in brain serotonin levels.
"
2.
Tremor (Tremors)
08/21/1987 - "
Benzodiazepine receptors are involved in tabernanthine-induced tremor: in vitro and in vivo evidence.
"
08/21/1987 - "
Moreover, tabernanthine-induced tremor was inhibited reversibly by flunitrazepam or by Ro-15 1788 (an antagonist of benzodiazepine-receptors).
"
08/21/1987 - "
In vivo, both tabernanthine and carbolines cause a fine general tremor, suggesting that a possible interaction with benzodiazepine receptors could be involved in the activity of tabernanthine.
"
3.
Hypotension (Low Blood Pressure)
11/01/1981 - "
1. Tabernanthine produced, in anaesthetized Rat and Dog, bradycardia and hypotension which remained after atropine or vagotomy.
"
4.
Bradycardia
11/01/1981 - "
3. Bradycardia occurred also after per os tabernanthine administration in unanaesthetized Dog.
"
11/01/1981 - "
1. Tabernanthine produced, in anaesthetized Rat and Dog, bradycardia and hypotension which remained after atropine or vagotomy.
"
Related Drugs and Biologics
1.
Serotonin (5 Hydroxytryptamine)
2.
GABA-A Receptors (GABA(A) Receptor)
3.
Flunitrazepam (Rohypnol)
4.
Carbolines (Beta-Carbolines)
5.
Atropine
Related Therapies and Procedures
1.
Vagotomy