|1.||Al-Eryani, Laila: 2 articles (09/2014 - 08/2014)|
|2.||Clair, Heather B: 2 articles (09/2014 - 08/2014)|
|3.||Wahlang, Banrida: 2 articles (09/2014 - 08/2014)|
|4.||Prough, Russell A: 2 articles (09/2014 - 08/2014)|
|5.||Cave, Matthew C: 2 articles (09/2014 - 08/2014)|
|6.||Imbeault, Pascal: 2 articles (05/2002 - 03/2002)|
|7.||Tremblay, Angelo: 2 articles (05/2002 - 03/2002)|
|8.||Mauriège, P: 2 articles (04/2002 - 11/2001)|
|9.||Imbeault, P: 2 articles (04/2002 - 11/2001)|
|10.||Tremblay, A: 2 articles (04/2002 - 11/2001)|
|1.||Hepatocellular Carcinoma (Hepatoma)
05/01/1985 - "Thus, within the Sprague-Dawley rat group exposed to a diet with relatively high concentrations of Aroclor 1260 for 2 years a hepatocarcinogenic effect manifested by formation of slowly growing hepatocellular carcinomas was produced."
08/01/2014 - "This study evaluates Aroclor 1260, a PCB mixture with congener composition mimicking that of human adipose tissue, and selected congeners, as potential ligands for these receptors utilizing human hepatoma-derived (HepG2) and primate-derived (COS-1) cell lines, and primary human hepatocytes. "
09/15/2014 - "The purpose of this study was to evaluate the hepatic effects of a PCB mixture, Aroclor 1260, whose composition mimics human bioaccumulation patterns, in a mouse model of diet-induced obesity (DIO). "
09/15/2014 - "Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease."
|3.||Weight Loss (Weight Reduction)
11/01/2001 - "In men, higher the increase in basal lipolysis of subcutaneous abdominal or femoral adipocytes, greater the rise in plasma levels of most pollutants (HCB, Aroclor 1260, PCBs 118, 138 and 153) was in response to weight loss (0.51<r<0.70, P<0.05). "
11/01/2001 - "In response to weight loss, significant increases of all organochlorines investigated were observed in men, whereas only p,p'-DDE, Aroclor 1260, PCBs 153 and 180 significantly rose in women. "
04/01/2002 - "In men, relationships between changes in plasma HCB, Aroclor 1260, and PCB-153 concentrations and those in fasting insulin levels in response to weight loss remained significantly correlated after correction for fat mass loss (-.46 < partial r < -.51, P values ranging from.05 to.07). "
03/01/2002 - "Vastus lateralis skeletal muscle enzyme activities and plasma OC (Aroclor 1260, polychlorinated biphenyl 153, p,p'-DDE, beta-hexachlorocyclohexane, and hexachlorobenzene) were measured before and after a weight loss program in 17 men and 20 women. "
04/01/2002 - "Fasting insulin and the area under the curve (AUC) of insulin after a 75-g oral glucose load, plasma levels of 1 commercial polychlorinated biphenyl (PCB) mixture (Aroclor 1260), 1 PCB congener (PCB 153), and 3 pesticides (2,2'-bis(4-chlorophenyl)-1,1-dichloroethylene (p,p'-DDE), beta-hexachlorocyclohexane (beta-HCH), and hexachlorobenzene (HCB)) were measured before and after a 15-week weight loss program induced by a caloric restriction in a sample of obese men and women. "
12/15/2000 - "The hepatic tumor promoting activity of the planar 0-1 ortho ( approximately 9.7% w/w) and the nonplanar 2-4 ortho ( approximately 90.3% w/w) fraction of the commercial PCB mixture Aroclor 1260 was studied using a medium-term two-stage initiation/promotion bioassay in female Sprague-Dawley rats. "
02/01/1988 - "Induction of liver tumors in male Wistar rats by feeding polychlorinated biphenyls (Aroclor 1260)."
01/01/1998 - "The incidence of hepatocellular neoplasms was highly sex-dependent (females >> males), differed between Aroclor mixtures and, for females, increased with dose and followed the general incidence pattern of Aroclor 1254 > Aroclor 1260 approximately Aroclor 1242 > Aroclor 1016. "
|5.||Body Weight (Weight, Body)
12/01/1999 - "Treatment with Aroclor 1260 at dosages ranging from 0.5 to 50 mg/kg/day had no effect on body weight, but liver weight was increased significantly in rats treated with the two highest dosages. "
10/01/2000 - "Single intraperitoneal (ip; 10 mg/kg body weight) or bilateral intratesticular (itt; 25 microg/testis) injections of Askarel markedly decreased serum androgen levels 24 hr after administration. "
10/01/1994 - "The commercial polychlorinated biphenyl (PCB) formulation Aroclor 1260 (4 mg/kg body weight), technical grade dichlorodiphenyltrichloroethane (DDT; 3 mg) and Lindane (gamma-hexachlorocyclohexane; 0.8 mg) were administered orally, either separately or in combination, to sexually mature female rabbits three times per week for 12-15 weeks. "
|4.||Polychlorinated Biphenyls (PCBs)
|6.||Dichlorodiphenyl Dichloroethylene (DDE)
|7.||Chlorodiphenyl (54% Chlorine)
|8.||Cytochrome P-450 CYP1A2 (CYP1A2)
|9.||Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)