delta-lactone 6-iodo-5-hydroxy-eicosatrienoic acid (IL-delta)
Also Known As:
IL-delta; 6-iodo-5-hydroxy-eicosatrienoic acid, delta-lactone; 5-hydroxy-6-iodo-8,11,14-eicosatrienoic acid delta lactone; 6-delta-iodo-lactone; 6-delta-iodolactone; 6-iodo-delta-lactone
Networked: 4
relevant articles (0 outcomes,
1 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Pilecki, Stanisław E:
1 article
(01/2012)
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2. | Swietaszczyk, Cyprian:
1 article
(01/2012)
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3. | Cabrini, Romulo L:
1 article
(09/2010)
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4. | Dagrosa, María A:
1 article
(09/2010)
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5. | Fernandez, Marina:
1 article
(09/2010)
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6. | Juvenal, Guillermo J:
1 article
(09/2010)
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7. | Oglio, Romina:
1 article
(09/2010)
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8. | Pisarev, Mario A:
1 article
(09/2010)
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9. | Randi, Andrea S:
1 article
(09/2010)
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10. | Thomasz, Lisa:
1 article
(09/2010)
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Related Diseases
1. | Goiter
09/01/2010
- " The goiter inhibitory action of IL-delta is due to the inhibition of cell proliferation and the transient stimulation of apoptosis. " 06/02/1994
- " The thyroid gland synthesizes 6-delta-iodolactone, a compound shown to inhibit goiter growth in vivo and cell proliferation in culture. " 01/01/2012
- " One of the compounds, 6-iodo-5-hydroxy-eicosatrienoic acid delta-lactone (6-IL), is believed to inhibit goiter growth, to modulate the cell response on some growth factors, and to trigger apoptosis in some types of cells. " 09/01/2010
- " The inhibitory action of IL-delta on goiter formation was accompanied by the inhibition of cell proliferation evidenced by a significant decrease in cell number, PCNA expression, and asymmetry of the ploidy histograms. " 09/01/2010
- " We have demonstrated that the administration of delta-iodolactone (i.e., 5-iodo-delta lactone) of arachidonic acid (IL-delta), a mediator in thyroid autoregulation, prevents goiter induction by methylmercaptoimidazol (MMI) in rats. "
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