|1.||Saadi, Irfan: 2 articles (02/2014 - 11/2013)|
|2.||Sarup, Alan: 2 articles (02/2005 - 08/2002)|
|3.||Bolvig, Tina: 2 articles (02/2005 - 08/2002)|
|4.||White, H Steve: 2 articles (02/2005 - 08/2002)|
|5.||Larsson, Orla M: 2 articles (02/2005 - 08/2002)|
|6.||Schousboe, Arne: 2 articles (02/2005 - 08/2002)|
|7.||Petersen, Gitte: 2 articles (02/2005 - 08/2002)|
|8.||Frølund, Bente: 2 articles (02/2005 - 08/2002)|
|9.||Krogsgaard-Larsen, Povl: 2 articles (02/2005 - 08/2002)|
|10.||de Vries, Andrica C H: 1 article (07/2015)|
01/01/1983 - "THPO was also effective in preventing seizures induced in epileptic chicks by intermittent photic stimulation. "
07/01/1989 - "THPO failed to increase PTZ seizure thresholds. "
05/06/1983 - "THPO (4,5,6,7-tetrahydroisoxazolo[4.5-c]pyridin-3-ol), 1-5 mumol i.c.v. or 1-4 mmol/kg i.p., protects against sound-induced seizures. "
05/06/1983 - "There is no protection against pentylenetetrazol seizures after i.c.v. THPO injection, but THPO, 2-8 mmol/kg i.p., is protective. "
08/01/2002 - "exo-THPO, its alkylated analogs, and tiagabine displayed a time- and dose-dependent inhibition of audiogenic seizures after i.c.v. administration. "
02/01/2014 - "Consistent with two of three previously described patients, our patient also presents with thrombocytopenia, which we postulate is caused by haploinsufficiency of THPO. "
09/01/2008 - "The first generation thrombopoietic agents, recombinant THPO and 'megakaryocyte growth and development factor' (PEG-rHuMGDF) entered clinical trials, but their development was discontinued owing to neutralizing auto-antibodies cross-reacting with endogenous THPO, causing thrombocytopenia in healthy volunteers. "
04/01/2015 - "The thrombopoietin receptor agonists (THPO-RAs), romiplostim and eltrombopag, are effective and safe in immune thrombocytopenia (ITP). "
|3.||Hepatocellular Carcinoma (Hepatoma)
09/01/2009 - "The list included well-known tumor-associated NTRK1, FGF8, TP53, and TGFbeta1 genes and potentially novel oncogenes such as THPO (3q27.1), JMJD1B, and EGR1 (5q31.2), which was investigated in this study. "
07/01/2008 - "Moreover, novel fields to explore possible roles of the THPO variants are opened by observations that this hormone can influence the formation of hematopoietic progenitors and its expression occurs in some tumors as well as in tissues not directly related to the thrombopoiesis. "
05/01/2008 - "A mutation in THPO occurred de novo in the same position as in a previously described family with hereditary thrombocythemia. "
05/01/2008 - "Here we characterized a THPO mutation in a hereditary thrombocythemia pedigree with 11 affected family members. "
07/01/2015 - "We report, for the first time, a non-syndromic infant with a reversible myeloproliferative disease that harbors a germline hereditary thrombopoietin (THPO) gene mutation, a condition that is known to induce familial thrombocytosis at increasing age. "
07/01/2012 - "Hereditary thrombocythemia (HT) has been described as a rare benign disorder caused by mutations in the thrombopoietin (THPO) or the c-Mpl receptor genes. "
05/01/2008 - "Affected family members carry a G --> C transversion in the splice donor of intron 3 of THPO that co-segregated with thrombocytosis within the pedigree. "
|4.||Inosine Triphosphate (ITP)
|10.||Thrombopoietin (c-mpl Ligand)
|1.||Platelet Transfusion (Blood Platelet Transfusions)