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molephantinin
germacranolide from Elephantopus mollis; RN given refers to (3aR-(3aR*,4S*(E),6E,9Z,11S*,11aS*))-isomer; structure in first source
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Terpenes: 1461
Sesquiterpenes: 1370
molephantinin: 2
Related Diseases
1.
Carcinoma (Carcinomatosis)
06/01/1982 - "
The principle effect of molephantinin on Ehrlich ascites carcinoma cells was to depress DNA and protein synthesis both in vivo and in vitro.
"
09/01/1980 - "
Preliminary in vivo tumor assays indicated that molephantinin and phantomolin were potent inhibitors of Ehrlich ascites carcinoma and Walker 256 carcinosarcoma.
"
2.
Ascites
06/01/1982 - "
The principle effect of molephantinin on Ehrlich ascites carcinoma cells was to depress DNA and protein synthesis both in vivo and in vitro.
"
09/01/1980 - "
Preliminary in vivo tumor assays indicated that molephantinin and phantomolin were potent inhibitors of Ehrlich ascites carcinoma and Walker 256 carcinosarcoma.
"
06/01/1982 - "
Antitumor agents LII: The effects of molephantinin on nucleic acid and protein synthesis of Ehrlich ascites cells.
"
3.
Neoplasms (Cancer)
09/01/1980 - "
Preliminary in vivo tumor assays indicated that molephantinin and phantomolin were potent inhibitors of Ehrlich ascites carcinoma and Walker 256 carcinosarcoma.
"
4.
Lymphoid Leukemia
09/01/1980 - "
Molephantinin also showed significant antileukemic activity in the P-388 lymphocytic leukemia screen.
"
5.
Carcinosarcoma
09/01/1980 - "
Preliminary in vivo tumor assays indicated that molephantinin and phantomolin were potent inhibitors of Ehrlich ascites carcinoma and Walker 256 carcinosarcoma.
"
Related Drugs and Biologics
1.
Proteins (Proteins, Gene)
2.
Nucleic Acids
3.
DNA (Deoxyribonucleic Acid)
4.
Antineoplastic Agents (Antineoplastics)
5.
phantomolin