16-methyl-20-methoxy-PGE2

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3 relevant articles (0 outcomes, 0 trials/studies) found for this Bio-Agent

Description: has strong inhibitory effect on IgE(mouse)-mediated passive cutaneous anaphylaxis; RN given refers to (5Z,11alpha,13E,15S,16S)-isomer

Also Known As:

16(S)-methyl-20-methoxy-PGE2; 16(S)-methyl-20-methoxyprostaglandin E2; YPG 209; YPG 209, (5Z,11allpha,13E,15R,16S)-isomer; YPG 209, (5Z,11alpha,13E,15S)-isomer; YPG-209

Bio-Agent Context: Research Results

Related Diseases

1.	Seizures (Seizure) 02/01/1981 - "Thiopental-induced sleeping time in mice was prolonged by oral administration of YPG-209 in a dose of 300 micrograms/kg. On the other hand, spontaneous EEG and EEG arousal response in gallamine-immobilized cats were not affected by intravenous administration of YPG-209 in a dose of 100 micrograms/kg. Mice taming effect, rota rod performance and drug- or electroshock-induced convulsions were not affected by oral administration of YPG-209 in a dose of 3 mg/kg. Methamphetamine-induced lethality in mice was inhibited by subcutaneous administration of YPG-209 in a dose of 5 mg/kg. Normal rectal temperature in mice was lowered by oral administration of YPG-209 in a dose of 5 mg/kg. Normal rectal temperature in mice was lowered by oral administration of YPG-209 in a dose of 100 micrograms/kg. The central pharmacological actions of PGE2 were qualitatively similar to those of YPG-209, but the potencies of central actions of PGE2 were less than those of YPG-209" Order ALL the reference details at left...
2.	Hypotension (Low Blood Pressure) 04/01/1977 - "Neither hypotension nor diarrhea could be observed at the doses of YPG-209 exhibiting a considerable bronchodilator effect" Order ALL the reference details at left...
3.	Hypersensitivity (Allergy) 03/01/1980 - "The effects of 16(S)-methyl-20-methoxy-PGE2 (YPG-209) on hypersensitivity reactions were investigated in the rat, guinea-pig and mouse" 03/01/1980 - "Inhibition of hypersensitivity reactions by 16(S)-methyl-20-methoxy-PGE2 (YPG-209) in animals." 03/01/1980 - "The oral doses of YPG-209 diminished both histamine and 5-hydroxytryptamine hypersensitivity of the Bordetella pertussis-treated mice" Order ALL the reference details at left...
4.	Diarrhea 04/01/1977 - "Neither hypotension nor diarrhea could be observed at the doses of YPG-209 exhibiting a considerable bronchodilator effect" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Dinoprostone (PGE2)
2.	Thiopental (Pentothal)
3.	Serotonin (5 Hydroxytryptamine)
4.	Methamphetamine (Desoxyn)
5.	Histamine (Histamine Dihydrochloride)
6.	Gallamine Triethiodide (Gallamine)

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