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N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

NAGPA (EC 3.1.4.45), also known as the uncovering enzyme, is localized in the trans-Golgi network, where it removes a covering N-acetylglucosamine from the mannose 6-phosphate recognition marker on lysosomal acid hydrolases; RefSeq NM_016256 (human)
Also Known As:
GlcNAc-1-phosphodiester alpha-N-acetylglucosaminidase; GlcNAc-1-phosphodiester-N-acetylglucosaminidase, mouse; N-acetylglucosamine-1-phosphodiester N-acetylglucosaminidase; N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, human; NACGL phosphodiesterase; NAGPA protein, human; alpha-N-acetylglucosaminyl phosphodiesterase; alpha-N-acetylglucosaminyl phosphodiesterase, rat; mannose 6-phosphate-uncovering enzyme; uncovering enzyme
Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Lee, Wang-Sik: 1 article (11/2011)
2. Kornfeld, Stuart: 1 article (11/2011)
3. Drayna, Dennis: 1 article (11/2011)
4. Kang, Changsoo: 1 article (11/2011)

Related Diseases

1. Stuttering (Stammering)
2. Mucolipidoses (Sialidosis)

Related Drugs and Biologics

1. Mannose (D-Mannose)