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diethylmethylnitrosourea

structure in first source

Also Known As:

1,1-diethyl-3-methyl-3-nitrosourea; 3,3-diethyl-1-methyl-1-nitrosourea; DEMNU; N,N-diethyl-N'-methyl-N'-nitrosourea; nitrosomethyldiethylurea

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Nitrosourea Compounds: 21
      - diethylmethylnitrosourea: 4
- Nitroso Compounds: 446
  - Nitrosourea Compounds: 21
    - diethylmethylnitrosourea: 4

Related Diseases

1.	Neoplasms (Cancer) 01/01/1990 - "The pre- and postnatal administration of DEMNU induces a high frequency of tumors when applied via the intravenous route, and the latency periods show a dose dependence (table I). " 06/01/1980 - "Neither nitrosoheptamethyleneimine nor nitrosomethyldiethylurea seemed to induce tumors in guinea pigs under our conditions." 08/08/1975 - "Tumors of nervous origin arose after treatment with nitrosotrimethylurea (3/30), notrosotriethylurea (7/30), nitrosomethyldiethylurea (23/30), and nitrosoethyldimethylurea (8/30). " 08/01/1980 - "Nitrosomethyldiethylurea induced almost exclusively a high incidence of both astrocytomas of the brain and tumors of the spinal cord."
2.	Astrocytoma (Pilocytic Astrocytoma) 08/01/1980 - "Nitrosomethyldiethylurea induced almost exclusively a high incidence of both astrocytomas of the brain and tumors of the spinal cord."

Related Therapies and Procedures

1.	Aftercare (After-Treatment)