|1.||Aguilera, Andrés: 9 articles (10/2014 - 04/2006)|
|2.||García-Rubio, María L: 4 articles (10/2014 - 10/2006)|
|3.||Luna, Rosa: 3 articles (10/2014 - 10/2006)|
|4.||Santos-Pereira, José M: 2 articles (10/2014 - 11/2013)|
|5.||Wellinger, Ralf E: 2 articles (10/2006 - 04/2006)|
|6.||González-Aguilera, Cristina: 1 article (10/2014)|
|7.||Nakayama, Kei: 1 article (07/2014)|
|8.||Shiina, Nobuyuki: 1 article (07/2014)|
|9.||Barroso, Sonia I: 1 article (07/2014)|
|10.||Bhatia, Vaibhav: 1 article (07/2014)|
06/29/1983 - "A few mRNAs in S-180 ascites cells are found as non-polysomal messenger ribonucleoprotein particles, whose translation is restricted both in vivo and in vitro. "
04/15/1982 - "Functional characteristics of untranslated messenger ribonucleoprotein particles from mouse sarcoma ascites cells. "
05/01/1983 - "In the present report we summarize recent results concerning our studies on messenger ribonucleoprotein particles and RNA-binding proteins from the cytoplasm of mouse erythroblasts and mouse Krebs II ascites cells."
08/25/1979 - "Distribution of cytoplasmic poly(A+)RNA sequences in free messenger ribonucleoprotein and polysomes of mouse ascites cells."
08/25/1979 - "Characterization of poly(A+)RNA in free messenger ribonucleoprotein and polysomes of mouse Taper ascites cells."
02/01/2011 - "To understand the mechanisms that generate genome instability mediated by mRNP biogenesis impairment and by AID, we devised a yeast chromosomal system based on different segments of mammalian S regions and c-MYC for the analysis of chromosomal rearrangements in both wild-type and THO mutants. "
08/01/2010 - "The interplay between transcription and mRNP formation feeds forward and backward and involves a number of conserved factors, from THO to THSC/TREX-2, which in addition have a unique impact on transcription-dependent genome instability. "
10/01/2006 - "To get more insight into the interconnection between mRNP biogenesis and genomic instability, we searched for HPR1 mutations that differentially affect gene expression and recombination. "
04/01/2006 - "Our results link transcription-dependent genomic instability in THO mutants with impaired replication fork progression, suggesting a molecular basis for a connection between inefficient mRNP biogenesis and genetic instability."
02/01/2011 - "Our study not only provides new clues to understand the role of mRNP biogenesis in preventing genome rearrangements and the mechanism of AID-mediated genome instability, but also shows that, once uracil residues are produced by AID-mediated deamination, these are processed into DSBs and chromosomal rearrangements by the general and conserved DNA repair functions present from yeast to human cells."
01/01/2011 - "This study opens the possibility of defining mRNP biogenesis factors as putative players in cell proliferation that could contribute to tumor development."
11/15/2013 - "Therefore, our work demonstrates that mRNP factors are critical for genome integrity and opens the option of using them as therapeutic targets in anti-cancer treatment. "
01/01/2011 - "We show that the expression of two mRNP factors, THOC1 and ALY are altered in several tumor tissues. "
01/01/2011 - "Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers."
11/28/2006 - "WT1 was also shown to be present in nuclear mRNP particles suggesting that in leukaemia, and by extension in all cancers in which it is involved, WT1 works both at the DNA and mRNA target level."
|4.||Neurodegenerative Diseases (Neurodegenerative Disease)
01/01/2014 - "Analysis of mRNP granules in their various contexts has revealed common themes of assembly, disassembly, and modes of mRNA regulation, yet new studies continue to reveal unexpected and important findings, such as links between aberrant mRNP granule assembly and neurodegenerative disease. "
02/01/2010 - "Our data define Plasmodium P granules as an ancient mRNP whose protein core has remained evolutionarily conserved from single-cell organisms to germ cells of multi-cellular animals and stores translationally silent mRNAs that are critical for early post-fertilization development during the initial stages of mosquito infection. "
05/22/1984 - "These results indicate a dual role of the mRNP in regulating protein synthesis during infection. "
09/01/1983 - "The effect of poliovirus infection on the translation in vitro of VSV messenger ribonucleoprotein particles."
10/01/1979 - "Late after infection of KB cells with adenovirus 5 an extra protein becomes associated with messenger ribonucleoprotein particles present in the polysomes. "
12/01/2007 - "To circumvent this inherent limitation of traditional gene expression profiling methods, an innovative mRNP-tagging technique was implemented to isolate host mRNA specifically from infected cells in vitro as well as in vivo following Venezuelan equine encephalitis virus (VEE) infection. "
|1.||Messenger RNA (mRNA)
|2.||RNA-Binding Proteins (RNA-Binding Protein)
|5.||Proteins (Proteins, Gene)
|6.||RNA (Ribonucleic Acid)
|9.||Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)