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dolichol pyrophosphate

Also Known As:

dolichol diphosphate; dolichyl pyrophosphate

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Welti, Michael: 1 article (01/2013)

Related Diseases

1.	Congenital Disorders of Glycosylation 01/01/2013 - "In the majority of congenital disorders of glycosylation, the assembly of the glycan precursor GlcNAc(2)Man(9)Glc(3) on the polyprenol carrier dolichyl-pyrophosphate is compromised. "
2.	Neoplasms (Cancer) 01/01/1982 - "This is the first demonstration that normal and tumor mammary cells have dolichol diphosphate-bound oligosaccharides with very similar, if not identical, structures. " 01/01/1982 - "The main dolichol diphosphate-bound oligosaccharides present in primary cultures of both normal and tumor mouse mammary epithelial cells had the same size, yielded the same pattern after acetolysis and paper chromatography, had the same number of mannose residues susceptible to alpha-mannosidase degradation, and were composed of the same monosaccharide residues. "
3.	Hepatocellular Carcinoma (Hepatoma) 01/01/1985 - "In the presence of exogenous dolichyl phosphate mixture (18 and 19 isoprene units) the synthesis of dolichyl pyrophosphate N-acetylglucosamine and dolichyl phosphate mannose increased 3 times both in the liver and Hepatoma MC-29, while the formation of dolichyl phosphate glucose was 4 fold higher in the liver and 6-fold higher in Hepatoma MC-29. "
4.	Cystic Fibrosis (Mucoviscidosis) 10/08/1982 - "In contrast, the incorporation of mannose from GDPmannose into lipid fractions containing dolichol phosphate and dolichol pyrophosphate oligosaccharides as well as the incorporation of mannose from dolichol phospho[3H]mannose into both glycoproteins and dolichol derivatives were not significantly different among cell preparations from patients with cystic fibrosis and normal controls. "

Related Drugs and Biologics

1.	Mannose (D-Mannose)
2.	Oligosaccharides
3.	alpha-Mannosidase (LAMAN)
4.	Polysaccharides (Glycans)
5.	Phosphates (Orthophosphate)
6.	Monosaccharides
7.	Lipids
8.	Glycoproteins (Glycoprotein)
9.	Glucose (Dextrose)
10.	Dolichols