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Pseudechis venom

from Australian elapid snake; Pa ID neurotoxin has been sequenced; contains 68 amino acid residues

Also Known As:

Pa ID neurotoxin; Pa-11; Pa-13; pseudexin

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Complex Mixtures: 1906
- Venoms: 4328
  - Snake Venoms: 1139
    - Elapid Venoms: 169
      - Pseudechis venom: 3
Biological Factors: 2472
- Biological Toxins: 20
  - Venoms: 4328
    - Snake Venoms: 1139
      - Elapid Venoms: 169
        Pseudechis venom: 3

Related Diseases

1.	Paralysis (Palsy) 01/01/1989 - "It is concluded that Pa-10A and Pa-11 produce muscle paralysis by reducing acetylcholine release and by a direct blockade of muscle fibre contractility. "
2.	Neoplasms (Cancer) 01/01/1985 - "Exposure to PA-11 tumor cells in vivo also did not cause suppression of NK activity. " 01/01/1985 - "Exposure to PA-11 tumor cells, supernatants from cultured tumor cells, or sera from rats with advanced PA-11 in vitro did not result in inhibition of NK activity. " 01/01/1985 - "Cultured PA-11 tumor cells were shown to be resistant to NK lysis in vitro, and enhancement or inhibition of NK reactivity in vivo using drugs or antiserum did not change the rate or extent of metastasis evident at autopsy. "
3.	Neoplasm Metastasis (Metastasis) 01/01/1985 - "Cultured PA-11 tumor cells were shown to be resistant to NK lysis in vitro, and enhancement or inhibition of NK reactivity in vivo using drugs or antiserum did not change the rate or extent of metastasis evident at autopsy. "
4.	Body Weight (Weight, Body) 01/01/1985 - "Pa-11 was lethal to mice (LD50 0.23 micrograms/g body weight), whereas Pa-13 showed no lethal activity at a dose level of 7.4 micrograms/g mouse. "

Related Drugs and Biologics

1.	Pseudechis venom
2.	Acetylcholine (Acetylcholine Chloride)