|1.||Hudson, David M: 2 articles (01/2011 - 01/2010)|
|2.||Eyre, David R: 2 articles (01/2011 - 01/2010)|
|3.||Weis, Maryann: 1 article (01/2011)|
|4.||Kashiwazaki, Kazuo: 1 article (03/2010)|
|5.||Saito, Junichi: 1 article (03/2010)|
|6.||Sato, Ataru: 1 article (03/2010)|
|7.||Maruta, Akie: 1 article (03/2010)|
|8.||Imamura, Yasutada: 1 article (03/2010)|
|9.||Kitagawa, Yuko: 1 article (03/2010)|
|10.||Wada, Norihito: 1 article (03/2010)|
10/01/1994 - "to observe the influence of aging on urinary secretion of 3-hydroxyproline (3-Hyp) in normal subjects and in cancer patients and study the effects of aging on the accuracy of urinary 3-Hyp as a general-purpose cancer screening test. "
03/01/2010 - "We reported that endogenous urinary 3-hydroxyproline (3-Hyp) is useful for cancer screening because cancer invasion involves the destruction of basement membrane. "
10/01/1994 - "[Effects of aging on urinary secretion of 3-hydroxyproline and its importance for cancer screening in the elderly with ROC analysis]."
12/01/1992 - "Urinary 3-hydroxyproline level should be further investigated as a cancer screening method for healthy persons in the community or the workplace, but appears unlikely to detect many cancers in the earliest stages."
12/01/1992 - "Measurable 3-hydroxyproline peaks (by amino acid autoanalyzer) were absent from 93 samples from 211 healthy persons (44%), 50 of 99 patients with nonmalignant disease (50%), and 10 of 96 patients with cancer (10%). "
|2.||Osteogenesis Imperfecta (Lobstein Disease)
01/22/2010 - "No function is known for the much less common 3-hydroxyproline (3Hyp), although genetic defects inhibiting its formation cause recessive osteogenesis imperfecta. "
01/01/2011 - "Recessive mutations that prevent 3-hydroxyproline formation in type I collagen have been shown to cause forms of osteogenesis imperfecta. "
07/11/2008 - "The single 3-hydroxyproline residue in the collagen I polypeptides is essential for proper fibril formation and bone development as its deficiency leads to recessive osteogenesis imperfecta. "
|3.||Neoplasm Metastasis (Metastasis)
12/01/1992 - "The sensitivity of 3-hydroxyproline was 44% and higher than that of 4-hydroxyproline for the detection of stage II cancers (no distant metastasis); the sensitivities of both hydroxyprolines for the detection of stage I (very early cancer) were low. "
01/01/1982 - "4-hydroxyproline is increased in bone disease of Paget and in cancerous metastases of bone, 3-hydroxyproline is increased in case of polycystic kidney. "
|4.||Hereditary Nephritis (Alport Syndrome)
|5.||Polycystic Kidney Diseases (Polycystic Kidney Disease)
|1.||Hydroxyproline (4 Hydroxyproline)
|3.||Collagen Type IV (Type IV Collagen)
|4.||Collagen Type I (Type I Collagen)
|6.||Proteins (Proteins, Gene)