|1.||Nizet, Victor: 3 articles (06/2007 - 01/2002)|
|2.||Tsao, Nina: 2 articles (01/2015 - 08/2012)|
|3.||Kuo, Chih-Feng: 2 articles (01/2015 - 08/2012)|
|4.||Varki, Nissi: 2 articles (06/2007 - 05/2005)|
|5.||Puricelli, Jessica M: 1 article (10/2015)|
|6.||Park, Claudia J: 1 article (10/2015)|
|7.||Flaherty, Rebecca A: 1 article (10/2015)|
|8.||Lee, Shaun W: 1 article (10/2015)|
|9.||Higashi, Dustin L: 1 article (10/2015)|
|10.||Chen, Ying-Pin: 1 article (01/2015)|
10/01/2015 - "Streptolysin S Promotes Programmed Cell Death and Enhances Inflammatory Signaling in Epithelial Keratinocytes during Group A Streptococcus Infection."
11/01/2009 - "pyogenes mutant deficient in expression of the cytolytic toxin streptolysin S (SLS-) and evaluated events that occur during the first few hours of infection by using several models including injection of zebrafish (adults, larvae, and embryos), a transepithelial polymorphonuclear leukocyte (PMN) migration assay, and two-photon microscopy of mice in vivo. "
11/01/2009 - "Streptolysin S inhibits neutrophil recruitment during the early stages of Streptococcus pyogenes infection."
06/07/2007 - "Streptococcus iniae beta-hemolysin streptolysin S is a virulence factor in fish infection."
05/01/2005 - "Mutational analysis of the group A streptococcal operon encoding streptolysin S and its virulence role in invasive infection."
06/01/1977 - "Hemolysis of human erythrocytes produced by streptolysin S (SLS) was investigated. "
04/01/2002 - "Virtually all group A streptococci (GAS) produce streptolysin S (SLS), a cytolytic toxin that is responsible for the beta-hemolysis surrounding colonies of the organisms grown on blood agar. "
11/09/2001 - "Similarities between complement-mediated and streptolysin S-mediated hemolysis."
07/01/2000 - "Streptolysin S (SLS) is the cytolytic factor that creates the zone of beta-hemolysis surrounding GAS colonies grown on blood agar. "
06/01/1977 - "Hemolysis induced by streptolysin S: kinetics of hemoglobin and 86Rubidium release."
|3.||Rheumatic Fever (Acute Articular Rheumatism)
09/01/1983 - "Rheumatic fever has been associated with a streptococcal outbreak due to a nonhemolytic (streptolysin S-negative) strain. "
10/01/1982 - "The genetic determinant for streptolysin S production (SLS+) was successfully transduced to two naturally occurring nonhemolytic strains of group A streptococci (Streptococcus pyogenes), an M-type 18 strain associated with an outbreak of rheumatic fever and an M-negative variant of a type 49 strain isolated from a skin lesion. "
07/01/1969 - "Transformation of lymphocytes by streptolysin S as a test for rheumatic fever."
09/01/1968 - "Transformation of lymphocytes from patients with rheumatic fever by streptolysin S."
11/01/1964 - "THE ACTION OF STREPTOLYSIN S ON PERIPHERAL LYMPHOCYTES OF NORMAL SUBJECTS AND PATIENTS WITH ACUTE RHEUMATIC FEVER."
|4.||Pharyngitis (Sore Throat)
09/01/1950 - "Inhibition of streptolysin S by the serum of patients with rheumatic fever and acute streptococcal pharyngitis."
02/01/2010 - "Among nonhemolytic Streptococcus pyogenes (group A streptococcus) strains (n = 9) isolated from patients with pharyngitis or acute otitis media, we identified three deletions in the region from the epf gene, encoding the extracellular matrix binding protein, to the sag operon, mediating streptolysin S production."
01/01/2008 - "Streptolysin S (SLS) is a bacteriocin-like haemolytic and cytotoxic virulence factor that plays a key role in the virulence of Group A Streptococcus (GAS), the causative agent of pharyngitis, impetigo, necrotizing fasciitis and streptococcal toxic shock syndrome. "
09/01/1979 - "Strains of M-type 12 streptococci from 18 patients with acute glomerulonephritis and 18 patients with uncomplicated pharyngitis were analyzed for in vitro production of streptolysin O, diphosphopyridine nucleotidase, hyaluronidase, streptokinase, streptolysin S, proteinase, hyaluronic acid, and fibrinogen-precipitating factor. "
|5.||Streptococcal Infections (Streptococcal Infection)
12/01/1999 - "The possible role played by streptolysin S (SLS) of group A streptococci in the pathophysiology of streptococcal infections and in post-streptococcal sequelae is discussed. "
08/01/2012 - "Synergistic effects of streptolysin S and streptococcal pyrogenic exotoxin B on the mouse model of group A streptococcal infection."
08/01/2010 - "Superantigen and streptolysin S genes are the most important virulence factors contributing to an invasive streptococcal infection. "
|3.||Virulence Factors (Pathogenicity Factors)
|4.||Hyaluronic Acid (Hyaluronan)
|5.||Fibrinogen (Factor I)
|8.||Cysteine Proteases (Cysteine Protease)
|10.||Succinic Acid (Succinate)