streptolysin S

10/01/2019 - "Skin infection sites of streptolysin S-deficient MGAS2221 ΔsagA were full of neutrophils with nuclear staining, whereas MGAS2221 ΔsagA infection was not cleared. "
10/01/2015 - "Streptolysin S Promotes Programmed Cell Death and Enhances Inflammatory Signaling in Epithelial Keratinocytes during Group A Streptococcus Infection."
11/01/2009 - "pyogenes mutant deficient in expression of the cytolytic toxin streptolysin S (SLS-) and evaluated events that occur during the first few hours of infection by using several models including injection of zebrafish (adults, larvae, and embryos), a transepithelial polymorphonuclear leukocyte (PMN) migration assay, and two-photon microscopy of mice in vivo. "
11/01/2009 - "Streptolysin S inhibits neutrophil recruitment during the early stages of Streptococcus pyogenes infection."
05/01/2005 - "Mutational analysis of the group A streptococcal operon encoding streptolysin S and its virulence role in invasive infection."

01/01/2020 - "Live Cell Microscopy and Flow Cytometry to Study Streptolysin S-Mediated Erythrocyte Hemolysis."
11/04/2016 - "GCS secretes the hemolysis toxin (streptolysin S, SLS) that causes hemolysis in the host cells. "
01/18/2016 - "These results provide key insights into the mechanism of streptolysin S-mediated haemolysis and have implications for the development of treatments against GAS. "
01/18/2016 - "Activation of band 3 mediates group A Streptococcus streptolysin S-based beta-haemolysis."
06/01/1977 - "Hemolysis of human erythrocytes produced by streptolysin S (SLS) was investigated. "

01/01/2016 - "This protocol describes the design of a permeable membrane insert-based bacterial infection system to study the effects of Streptolysin S, a potent toxin produced by Group A Streptococcus, on human epithelial keratinocytes. "

09/01/1983 - "Rheumatic fever has been associated with a streptococcal outbreak due to a nonhemolytic (streptolysin S-negative) strain. "
10/01/1982 - "The genetic determinant for streptolysin S production (SLS+) was successfully transduced to two naturally occurring nonhemolytic strains of group A streptococci (Streptococcus pyogenes), an M-type 18 strain associated with an outbreak of rheumatic fever and an M-negative variant of a type 49 strain isolated from a skin lesion. "
07/01/1969 - "Transformation of lymphocytes by streptolysin S as a test for rheumatic fever."
09/01/1968 - "Transformation of lymphocytes from patients with rheumatic fever by streptolysin S."
11/01/1964 - "THE ACTION OF STREPTOLYSIN S ON PERIPHERAL LYMPHOCYTES OF NORMAL SUBJECTS AND PATIENTS WITH ACUTE RHEUMATIC FEVER."

12/01/1999 - "The possible role played by streptolysin S (SLS) of group A streptococci in the pathophysiology of streptococcal infections and in post-streptococcal sequelae is discussed. "
08/01/2012 - "Synergistic effects of streptolysin S and streptococcal pyrogenic exotoxin B on the mouse model of group A streptococcal infection."
01/01/2022 - "Streptolysin S targets the sodium-bicarbonate cotransporter NBCn1 to induce inflammation and cytotoxicity in human keratinocytes during Group A Streptococcal infection."
08/01/2010 - "Superantigen and streptolysin S genes are the most important virulence factors contributing to an invasive streptococcal infection. "