|1.||Ziegler, J: 2 articles (11/2001 - 01/2000)|
|2.||Inman, Martyn W: 1 article (02/2013)|
|3.||Groome, Nigel M: 1 article (02/2013)|
|4.||Kilner, Colin: 1 article (02/2013)|
|5.||Dondas, H Ali: 1 article (02/2013)|
|6.||Elboray, Elghareeb E: 1 article (02/2013)|
|7.||Grigg, Ronald: 1 article (02/2013)|
|8.||Phillips, Roger M: 1 article (02/2013)|
|9.||Tijet, Nathalie: 1 article (08/2002)|
|10.||Brash, Alan R: 1 article (08/2002)|
|1.||Breast Neoplasms (Breast Cancer)
01/01/1989 - "In particular, 2-mercaptoethanol reacted with 4 to afford deschloro vinyl thioether 13 as suggested by NMR spectral studies, a result that implicated allene-quinone 14 as the electrophilic species produced in solution from 4. Antiestrogen binding sites and estrogen receptors from MCF 7 human breast cancer cells interacted with 3 and 5 with affinities comparable to those of tamoxifen and 1, respectively; 5 was shown not to bind irreversibly with these sites. "
|2.||Dehydration (Water Stress)
01/12/1988 - "We propose that the biosynthesis of racemic cis-12-oxo-PDA proceeds by dehydration of the 13(S)-hydroperoxide to an allene oxide. "
07/01/2002 - "This enzyme catalyses dehydration of the hydroperoxide to an unstable allene oxide in the JA biosynthetic pathway. "
11/01/2001 - "To understand whether this "JA burst" is under transcriptional control, we cloned allene oxide synthase (AOS; EC 188.8.131.52), the enzyme that catalyzes the dehydration of 13(S)-hydroperoxy octadecatrienoic acid to an allene oxide, the first specific reaction in JA biosynthesis. "
12/10/1981 - "The data support the following conclusions: 1) 16 identical to 1 delta 2 is activated to the CoA ester; 2) 16 identical to 1 delta 2 is acted on by an isomerase to produce a 2,3-allene; 3) either 16 identical to 1 delta 2 or the allene, or both, are hydrated to yield a beta-keto-CoA thioester after rearrangement; 4) the beta-keto ester is reduced to the beta-hydroxyacyl-CoA; 5) dehydration of the beta-hydroxy ester gives rise to trans-delta 2-hexadecenoate which accumulates; and 6) accumulation of the latter results from the inhibition of enoyl-CoA reductase by the 2,3-allene. "
01/01/2000 - "The barley AOSs, expressed in bacteria as active enzymes, catalyze the dehydration of LOX-derived 9- as well as 13-hydroperoxides of polyenoic fatty acids to the unstable allene oxides. "
|3.||Prostatic Neoplasms (Prostate Cancer)
02/04/2013 - "We describe a new approach to highly functionalised derivatives that starts from allene gas and proceeds via the combination of a three-component Pd(0)-catalysed cascade with a one-pot, three-component carbophilic Pt(II) cascade linked to a stereoselective acid-catalysed Mannich-Michael reaction that generates complex cyclopropyl diindolylmethanes which show selective activity against prostate cancer cell lines."
|1.||Estrogen Receptor Modulators (Antiestrogen)
|4.||Mercaptoethanol (2 Mercaptoethanol)
|10.||Hydrogen Peroxide (Hydroperoxide)