HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

G(2) chalone

inhibits entry of mouse epidermal cells from G2 phase into mitosis; see also related G(1) chalone

Also Known As:

epidermal G2 chalone

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Chalones: 45
      - G(2) chalone: 6

Related Diseases

1.	Neoplasms (Cancer) 01/01/1981 - "The presence of epidermal G2 chalone was investigated by different immunochemical methods in normal urothelium and in tumors of the urinary bladder induced in rats with N-butyl-N-butanol-(4)-nitrosamine. " 01/01/1981 - "[Detection of squamous cell differentiation in experimental tumors of urothelium by using epidermal G2 chalone]." 08/01/1980 - "Epidermal G2 chalone was determined in induced rat lung tumors by the double immunodiffusion test or by immunoautoradiography. " 12/01/1980 - "The epidermal G2 chalone-like substance was present in urine of 7 out of 10 rats bearing the antigen-positive tumors of the urinary bladder."
2.	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/16/1978 - "Balb/c/nu nude mice transplanted with a moderately differentiated squamous cell carcinoma were injected intraperitoneally with different doses of aqueous skin extracts containing the epidermal G2 chalone. " 10/16/1978 - "The effect of the epidermal G2 chalone on the mitotic duration in nude mouse epidermis and in a transplanted squamous cell carcinoma." 01/01/1977 - "The results indicate that the species-non-specificity and the reversibility of the epidermal G2 chalone activity, previously demonstrated in both malignant and non-malignant animal tissues and in human epidermis, is to be found even in human epidermoid carcinomas in vitro. " 07/01/1978 - "In order to test the mitosis-inhibiting effect and the tissue specificity of the epidermal G2 chalone for tumour cells, extracts from hairless mouse epidermis were tested in short-term tissue cultures of cells from human respiratory tract epidermoid carcinomas and adenocarcinomas. "
3.	Metaplasia 08/01/1980 - "Thus the detection of epidermal G2 chalone can serve as marker of squamous cell metaplasia in the rat lung tissue."
4.	Carcinoma (Carcinomatosis) 07/01/1978 - "These results indicate that epidermal G2 chalone produced from mouse skin is tissue specific for human epidermoid tumour cells, and also indicate that a chalone test might be used as a diagnostic tool for poorly differentiated carcinomas to see whether they are of epidermoid origin or not."
5.	Adenocarcinoma 07/01/1978 - "In order to test the mitosis-inhibiting effect and the tissue specificity of the epidermal G2 chalone for tumour cells, extracts from hairless mouse epidermis were tested in short-term tissue cultures of cells from human respiratory tract epidermoid carcinomas and adenocarcinomas. "

Related Drugs and Biologics

1.	Antigens