|1.||Park, H J: 2 articles (03/2001 - 05/2000)|
|2.||Lee, K T: 2 articles (03/2001 - 05/2000)|
|3.||Jung, Ji Yun: 1 article (12/2015)|
|4.||Chun, Wonjoo: 1 article (12/2015)|
|5.||Son, Yonghae: 1 article (12/2015)|
|6.||Lee, Chul Won: 1 article (12/2015)|
|7.||Ju, Seong A: 1 article (12/2015)|
|8.||Lee, Chu: 1 article (12/2015)|
|9.||Kim, Young Woo: 1 article (12/2015)|
|10.||Ku, Sae Kwang: 1 article (12/2015)|
06/01/1999 - "HN saponin F (3) was most potent with IC50 value of 3.7x10(-5) M followed by 3-O-beta-D-glucopyranosyl-(1->3)-alpha-L-rhamnopyranosyl-(1->2)-beta-L-+ ++arabi nopyranosyl hederagenin 28-O-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyrano side (8), 3-O-beta-L-arabinopyranosyl hederagenin 28-O-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranoside (5), dipsacus saponin A (4), and hederagenin (1) on the classical pathway (CP) of complement system, while the saponins 3-5 did not show the inhibition of hemolysis and rather increase the hemolysis on the alternative pathway (AP). "
|2.||Colonic Neoplasms (Colon Cancer)
08/01/2002 - "This increase was much higher with hederagenin monodesmoside and markedly elevated in normal cells than in cancer cells."
05/01/2000 - "Hence, hederagenin and its 3-O-glycosides could be suitable for cancer treatment chemopreventive drugs."
01/01/2014 - "Hederagenin, a derivative of oleanolic acid isolated from the leaves of ivy (Hedera helix L.), has been shown to have potential anti-tumor activity. "
07/01/2005 - "The isolates and some chemical transformation products were evaluated biologically, and the presence of an arabinosyl moiety among the hederagenin glycosides evaluated was found to be important for the modulation of cytotoxic activity against cancer cells."
08/01/2002 - "It was observed that i) for a same sugar sequence, monodesmosides with oleanolic acid as aglycone exhibit higher cytotoxicity than those containing hederagenin, ii) the sugar sequence O-alpha-L-rhamnopyranosyl (1 --> 2)-alpha-L-arabinopyranoside at C3 induces strong cytotoxicity and might be identified as a basic sequence for anti-tumor activity of oleanolic acid monodesmosides. "
12/01/2015 - "Interestingly, results of the carrageenan-induced mouse hind paw edema assay showed an anti-edema effect of hederagenin. "
06/01/1999 - "At the oral dose of 100 mg/kg, several steroidal saponins and triterpenoid saponins such as hederagenin glycosides showed significant inhibition of ear edema (20-37% inhibition), though less potent than indomethacin and hydrocortisone."
|5.||Lipid Metabolism Disorders (Metabolism Disorders, Lipid)
01/01/2015 - "The statistical data have shown that hederagenin exhibits multiple pharmacological activities in the treatment of hyperlipidemia, antiplatelet aggregation, liver protection, and anti-inflammation, indicating that hederagenin may exert a protective effect on vascular walls by improving lipid metabolism disorders and lipid deposition. "
|2.||Complement System Proteins (Complement)
|9.||Glycyrrhetinic Acid (Po 12)