CCCGGG-specific type II deoxyribonucleases

type II endonucleases recognizing sequence 5'-CCCGGG-3'

Also Known As:

Cfr9I endonuclease; Pac25I endonuclease; SmaI restriction endonuclease; XcyI restriction endonuclease; XmaI restriction endonuclease; endodeoxyribonuclease Cfr9I; endodeoxyribonuclease Pac25I; endodeoxyribonuclease SmaI; endodeoxyribonuclease XcyI; endodeoxyribonuclease XmaI

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Deoxyribonucleases: 1259
        Endodeoxyribonucleases
        DNA Restriction Enzymes: 848
        Type II Site-Specific Deoxyribonucleases
        CCCGGG-specific type II deoxyribonucleases: 2
      - Endonucleases: 1227
        Endodeoxyribonucleases
        DNA Restriction Enzymes: 848
        Type II Site-Specific Deoxyribonucleases
        CCCGGG-specific type II deoxyribonucleases: 2
  - DNA Restriction-Modification Enzymes: 41
    - DNA Restriction Enzymes: 848
      - Type II Site-Specific Deoxyribonucleases
        CCCGGG-specific type II deoxyribonucleases: 2

Experts

1.	Alexeyev, M F: 1 article (04/2008)
2.	Bonilla, G: 1 article (04/2008)
3.	Pastukh, V: 1 article (04/2008)
4.	Shokolenko, I: 1 article (04/2008)
5.	Venediktova, N: 1 article (04/2008)
6.	Wilson, G L: 1 article (04/2008)
7.	Euler, Chad W: 1 article (02/2007)
8.	Fischetti, Vincent A: 1 article (02/2007)
9.	Martin, Judith M: 1 article (02/2007)
10.	Ryan, Patricia A: 1 article (02/2007)

Related Diseases

1.	Pharyngitis (Sore Throat) 02/01/2007 - "While screening the clonality of Streptococcus pyogenes isolates from an outbreak of erythromycin-resistant pharyngitis in Pittsburgh, PA, we found a correlation between the presence of the chimeric element Phi10394.4 (carrying the macrolide efflux gene, mefA) and genomic DNA being resistant to cleavage by SmaI restriction endonuclease. "
2.	Infections 04/01/2008 - "Here, we demonstrate that in cells heteroplasmic for the T8993G mutation, which is a cause for the NARP and MILS syndromes, infection with an adenovirus, which encodes the mitochondrially targeted R.XmaI restriction endonuclease, leads to selective destruction of mutant mtDNA. "

Related Drugs and Biologics

1.	Macrolides
2.	Erythromycin (Erycette)
3.	Elements
4.	Mitochondrial DNA (mtDNA)
5.	DNA (Deoxyribonucleic Acid)