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5-fluorouridine 5'-triphosphate
Also Known As:
FUTP; uridine 5'-(tetrahydrogen triphosphate), 5-fluoro-
Networked:
6
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
Pyrimidine Nucleotides: 48
Uracil Nucleotides: 40
Uridine Triphosphate: 442
5-fluorouridine 5'-triphosphate: 6
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleotides: 15763
Ribonucleotides: 307
Uracil Nucleotides: 40
Uridine Triphosphate: 442
5-fluorouridine 5'-triphosphate: 6
Pyrimidine Nucleotides: 48
Uracil Nucleotides: 40
Uridine Triphosphate: 442
5-fluorouridine 5'-triphosphate: 6
Related Diseases
1.
Tetraploidy
01/01/2023 - "
The FUTP method most effectively prevented apoptosis during porcine tetraploid embryo formation.
"
01/01/2023 - "
Three methods were investigated to produce tetraploid embryos: First, tetraploid embryos were produced using electro-fusion of two-cell stage parthenogenetic blastomere (FUTP).
"
01/01/2023 - "
The developmental competence of embryos, expression of trophectoderm cell marker genes, and distribution of YAP1 protein were investigated in tetraploid embryos produced using the FUTP method.
"
2.
Neoplasms (Cancer)
04/01/1988 - "
5-FU is metabolized to FUTP and FdUMP in tumor cells and exhibits RNA- and DNA-directed cytotoxicity.
"
3.
Inflammation (Inflammations)
01/01/2023 - "
This is in line with our findings that 5-FU generates FUTP which is incorporated into RNA, a mechanism known to underlie the myelosuppression and gastrointestinal inflammation associated with 5-FU.
"
4.
Hepatocellular Carcinoma (Hepatoma)
08/27/1981 - "
Hepatoma tissue culture cells, grown in the presence of D-galactosamine and 6-azauridine, demonstrate a strong reduction of the intracellular UTP pool that can be replenished by formation of UTP from uridine and FUTP from 5-fluorouridine within 2 h.
"
5.
Carcinoma (Carcinomatosis)
01/01/1988 - "
Parameters for inhibition of thymidylate synthase (TS) in a DMH-induced transplantable rat colon carcinoma were studied after intraperitoneal administration of bolus doxifluridine (5'-dFUR) 200 mg/kg. Levels of 5'-dFUR, 5-fluorouracil (5-FU), fluorouridinediphosphate (FUDP), and fluorouridinetriphosphate (FUTP) were determined by use of high-performance liquid chromatography.
"
Related Drugs and Biologics
1.
RNA (Ribonucleic Acid)
2.
Fluorouracil (Carac)
3.
Uridine Triphosphate (UTP)
4.
Uridine
5.
Thymidylate Synthase
6.
Proteins (Proteins, Gene)
7.
Galactosamine
8.
Fluorodeoxyuridylate
9.
DNA (Deoxyribonucleic Acid)
10.
Dimenhydrinate (DMH)