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4-methylhistamine

RN given refers to parent cpd

Also Known As:

4-methylhistamine dihydrochloride; 4-methylhistamine hydride; 1H-imidazole-4-ethanamine, 5-methyl-

Networked: 14 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Biogenic Amines: 992
    - Biogenic Monoamines: 29
      - Histamine: 13775
        Methylhistamines: 1
        4-methylhistamine: 14
  - Ethylamines: 5
    - Histamine: 13775
      - Methylhistamines: 1
        4-methylhistamine: 14
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - Histamine: 13775
        Methylhistamines: 1
        4-methylhistamine: 14

Experts

1.	Abd-Allah, Adel R A: 2 articles (07/2014 - 06/2014)
2.	Abdel-Hamied, Hala E: 2 articles (07/2014 - 06/2014)
3.	Ahmad, Sheikh Fayaz: 2 articles (07/2014 - 06/2014)
4.	Alrashidi, Ibrahim: 2 articles (07/2014 - 06/2014)
5.	Ashour, Abdelkader E: 2 articles (07/2014 - 06/2014)
6.	Attia, Sabry M: 2 articles (07/2014 - 06/2014)
7.	Bakheet, Saleh A: 2 articles (07/2014 - 06/2014)
8.	Zoheir, Khairy M A: 2 articles (07/2014 - 06/2014)
9.	Ho, Pil-Su: 1 article (07/2022)
10.	Mochizuki, Hidemi: 1 article (07/2022)

Related Diseases

1.	Pleurisy (Pleuritis) 07/01/2014 - "The aim of the present study was to determine the potential anti-inflammatory effect of 4-methylhistamine (4-MeH) or JNJ77777120 (JNJ) and to explore the role of H4R in a mouse model of carrageenan (Cg) -induced pleurisy. "
2.	Leukemia 02/28/2000 - "To study the effect of 4-methylhistamine on cytotoxicity of Ara-C for HL-60 leukemia cells in vitro. " 02/28/2000 - "[The negative effect of 4-methylhistamine, an H2 receptor agonist, on cytotoxicity of Ara-C for HL-60 leukemia cells]."
3.	Inflammation (Inflammations) 06/15/2007 - "We determined that the H4R agonist 4-methylhistamine when delivered intratracheally before Ag challenge mitigated airway hyperreactivity and inflammation. " 06/01/2016 - "Inhibitory Effect of Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice by Histamine H4 Receptor Agonist 4-Methylhistamine."
4.	Disease Progression 08/20/2023 - "Histamine H4 Receptor Agonist, 4-Methylhistamine, Aggravates Disease Progression and Promotes Pro-Inflammatory Signaling in B Cells in an Experimental Autoimmune Encephalomyelitis Mouse Model."
5.	Myocardial Ischemia (Ischemic Heart Diseases) 04/01/1988 - "We have investigated the effects of myocardial ischemia and exogenous histamine and 4-methylhistamine on the regulation of membrane bound alpha 2- and beta-adrenoreceptors (ARs) in the canine coronary artery smooth muscle (CAS). "

Related Drugs and Biologics

1.	Cytarabine (Cytosar-U)
2.	Carrageenan
3.	Histamine (Histamine Dihydrochloride)
4.	Histamine H4 Receptors
5.	Substance P
6.	Serotonin (5 Hydroxytryptamine)
7.	Histamine Receptors (Histamine Receptor)
8.	Peptides (Polypeptides)
9.	Peptide Hydrolases (Proteases)
10.	Pepsin A (Pepsin)

Related Therapies and Procedures

1.	Intradermal Injections