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sulindac sulfone (exisulind)

inhibits K-ras-dependent cyclooxygenase-2; sulfated analog of indomethacin;; CP248 is an antineoplastic agent that fosters microtubule depolymerization; structure in first source
Also Known As:
exisulind; (5-fluoro-2-methyl-1-(3,4,5-trimethoxybenzylidene)-3-(N-benzyl)-indene)-acetamide; 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfonyl)phenyl)methylene)-, (Z)-; Aptosyn; CP 248; CP248; FGN-1; OSIP 486823; OSIP-486823; OSIP486823; sulindac sulfone, (Z)-isomer
Networked: 89 relevant articles (10 outcomes, 37 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Thompson, W Joseph: 12 articles (07/2008 - 03/2002)
2. Weinstein, I Bernard: 10 articles (07/2008 - 04/2002)
3. Pamukcu, Rifat: 9 articles (10/2003 - 02/2002)
4. Pamukcu, R: 6 articles (11/2001 - 07/2000)
5. Bunn, Paul A: 5 articles (10/2007 - 02/2002)
6. Deguchi, Atsuko: 5 articles (01/2006 - 08/2002)
7. Piazza, Gary: 5 articles (05/2004 - 02/2002)
8. Thompson, W J: 5 articles (11/2001 - 07/2000)
9. Li, Han: 4 articles (07/2008 - 08/2002)
10. Xiao, Danhua: 4 articles (01/2006 - 04/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
3. Polyps
4. Prostatic Neoplasms (Prostate Cancer)
5. Disease Progression

Related Drugs and Biologics

1. sulindac sulfone (exisulind)
2. gemcitabine
3. Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)
4. Prostate-Specific Antigen (Semenogelase)
5. vinorelbine (Navelbine)
6. docetaxel (Taxotere)
7. sulindac sulfide
8. Carboplatin (JM8)
9. Sulindac (Copal)
10. Hormones

Related Therapies and Procedures

1. Chemoprevention
2. Prostatectomy (Retropubic Prostatectomy)
3. Heterologous Transplantation (Xenotransplantation)
4. Aftercare (After-Treatment)
5. Stents