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LY 117018

from Eli Lilly; less estrogenic & more estrogen-antagonistic than tamoxifen & trioxifene in rats & mice; LY 139478 is the HCl salt of LY 117018; LY 139478 is an estrogen agonist; structure in first source; a raloxifene analog
Also Known As:
6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl 4-(2-(1-pyrrolidinyl)ethoxy) phenyl ketone; LY 139478; LY-117018; LY-139478; LY117018; Lilly 117018; Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-
Networked: 24 relevant articles (2 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Jochems, Caroline: 2 articles (12/2009 - 10/2007)
2. Carlsten, Hans: 2 articles (12/2009 - 10/2007)
3. Wutzl, Arno: 1 article (11/2010)
4. Pietschmann, Peter: 1 article (11/2010)
5. Brosch, Susanne: 1 article (11/2010)
6. Brozek, Wolfgang: 1 article (11/2010)
7. Hofbauer, Günter: 1 article (11/2010)
8. Lernbass, Isolde: 1 article (11/2010)
9. Gruber, Reinhard: 1 article (11/2010)
10. Sanchez, Amelita: 1 article (08/2010)

Related Diseases

1. Metabolic Bone Diseases (Osteopenia)
2. Osteoporosis
3. Arthritis (Polyarthritis)
4. Postmenopausal Osteoporosis
5. Inflammation

Related Drugs and Biologics

1. Raloxifene (Evista)
2. Selective Estrogen Receptor Modulators (SERM)
3. Cyclosporine (Ciclosporin)
4. Estradiol (Estrace)
5. Estrogens (Estrogen)
6. Cytokines
7. salicylhydroxamic acid (SHAM)
8. Tamoxifen
9. Estrogen Receptor Modulators (Antiestrogen)
10. hydroxide ion

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)