bis(5-amidino-2-benzimidazolyl)methane

Subscribe to Selected New Research on bis(5-amidino-2-benzimidazolyl)methane

8 relevant articles (1 outcomes, 1 trials/studies) found for this Bio-Agent

Description: aromatic diamidine which has a significant suppressive effect on the cytopathology & yield of respiratory synctial (RS) virus; RN given refers to parent cpd

Also Known As:

BABIM; bis(5-amidino-2-benzimidazolyl)methane tetrachloride; 1H-Benzimidazole-5-carboximidamide, 2,2'-methylenebis-

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 23

2-Ring Heterocyclic Compounds

Benzimidazoles: 77

bis(5-amidino-2-benzimidazolyl)methane: 8

Related Diseases

1.	Arthritis (Polyarthritis) 09/01/1988 - "Bis(5-amidino-2-benzimidazolyl)methane, a powerful synthetic trypsin inhibitor, proved to be highly effective in suppressing the arthritis induced by streptococcal cell wall fragments in Lewis rats" 09/01/1988 - "Suppression of streptococcal cell wall-induced arthritis by a potent protease inhibitor, bis(5-amidino-2-benzimidazolyl)methane." 04/01/1990 - "This report builds on the authors' earlier discovery of bis(5-amidino-2-benzimidazolyl)methane (BABIM) as a strong suppressive agent for streptococcal cell wall fragment-induced arthritis in the Lewis rat" 04/01/1990 - "Sequential events in the pathogenesis of streptococcal cell wall-induced arthritis and their modulation by bis(5-amidino-2-benzimidazolyl)methane (BABIM)." Get all the results and reference details, order at left...
2.	Eosinophilia 12/01/1995 - "Therefore, in this study we examined the effects of two inhibitors of tryptase, APC 366 [N-(1-hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide hydrochloride] and BABIM [bis(5-amidino-2-benzimidazolyl)methane] on antigen-induced early and late responses, airway responsiveness as measured by carbachol provocation, microvascular permeability as measured by bronchoalveolar lavage (BAL) albumin concentrations, and tissue eosinophilia from biopsies in allergic sheep" Get all the results and reference details, order at left...
3.	Synovitis 10/01/1991 - "BABIM, on the other hand, was active against synovitis and osteitis, but not against splenic granuloma formation" 04/01/1990 - "Bis(5-amidino-2-benzimidazolyl)methane is shown to block acute synovitis, to retard and reduce granuloma formation in spleen and liver, to decrease neutrophilic leukocytosis, and to diminish hemopoietic hyperplasia in the bone, and thus also to mitigate the distinctive osteoclastic and chondroclastic events" Get all the results and reference details, order at left...
4.	Infection 10/01/1984 - "Suppression of respiratory syncytial virus infection in cotton rats by bis(5-amidino-2-benzimidazolyl)methane." 05/01/1984 - "One of the compounds, bis(5-amidino-2-benzimidazolyl)-methane, at a concentration of 10(-5) M demonstrated complete inhibition of plaque formation on day 6. Bis(5-amidino-2-benzimidazolyl)methane at the same concentration reduced cell injury even when added to the system after 72 h of rickettsial infection" Get all the results and reference details, order at left...
5.	Granuloma 10/01/1991 - "BABIM, on the other hand, was active against synovitis and osteitis, but not against splenic granuloma formation" 04/01/1990 - "Bis(5-amidino-2-benzimidazolyl)methane is shown to block acute synovitis, to retard and reduce granuloma formation in spleen and liver, to decrease neutrophilic leukocytosis, and to diminish hemopoietic hyperplasia in the bone, and thus also to mitigate the distinctive osteoclastic and chondroclastic events" Get all the results and reference details, order at left...
12 Diseases and 8 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Trypsin
2.	Tryptases (Tryptase)
3.	Carbachol (Carbastat)
4.	Antigens
5.	N- (1- hydroxy- 2- naphthoyl)arginyl- prolinamide
6.	prolinamide
7.	bis(5-amidino-2-benzimidazolyl)methane
8.	Protease Inhibitors (Protease Inhibitor)
9.	Peptide Hydrolases (Proteases)
10.	Urinary Plasminogen Activator (Urokinase)
11 Drugs and Important Bio-Agents and 5 more articles analyzed in the Research Interface, order at left...

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