ara-UTP

Also Known As:

arabinofuranosyluridine triphosphate; 2,4(1H,3H)-pyrimidinedione, 1-(5-O-(hydroxy((hydroxy(phosphonooxy)phosphinyl)oxy)phosphinyl)-beta-D-arabinofuranosyl)-

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidine Nucleotides: 48
      - Uracil Nucleotides: 40
        Uridine Triphosphate: 442
        ara-UTP: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Ribonucleotides: 307
    - Uracil Nucleotides: 40
      - Uridine Triphosphate: 442
        ara-UTP: 1
  - Pyrimidine Nucleotides: 48
    - Uracil Nucleotides: 40
      - Uridine Triphosphate: 442
        ara-UTP: 1

Related Diseases

Leukemia

07/01/1998 - "The present study demonstrated that circulating leukemia blasts accumulate ara-UTP during in vitro incubations with ara-C and during ara-C therapy."
07/01/1998 - "Intracellular accumulation of ara-CTP and ara-UTP in circulating leukemia blasts from six patients was quantitated by high-pressure liquid chromatography, revealing that ara-UTP accumulated during ara-C therapy. "
07/01/1998 - "Because other ara-U metabolites, especially the triphosphate (ara-UTP), may serve as additional effectors of cytotoxicity, the present study investigated whether ara-UTP accumulates in circulating leukemia blasts during ara-C therapy. "

Related Drugs and Biologics

1.	Cytarabine (Cytosar-U)
2.	Arabinofuranosyluracil (Ara U)
3.	triphosphoric acid (triphosphate)
4.	Arabinofuranosylcytosine Triphosphate

Related Therapies and Procedures

1.	Therapeutics